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Villonodular synovitis

villonodular synovitis, villonodular synovitis knee
Villonodular synovitis is a type of synovial swelling

Types include:

  • Pigmented villonodular synovitis PVNS
  • Giant cell tumor of the tendon sheath GCTS

Though they have very different names, they have the same histology, and stain positive for CD68, HAM56, and vimentin1

They are sometimes discussed together234


  1. ^ O'Connell JX, Fanburg JC, Rosenberg AE July 1995 "Giant cell tumor of tendon sheath and pigmented villonodular synovitis: immunophenotype suggests a synovial cell origin" Hum Pathol 26 7: 771–5 PMID 7628850 doi:101016/0046-81779590226-0 
  2. ^ Mackie GC November 2003 "Pigmented villonodular synovitis and giant cell tumor of the tendon sheath: scintigraphic findings in 10 cases" Clin Nucl Med 28 11: 881–5 PMID 14578700 doi:101097/01rlu0000093083778665c 
  3. ^ Maheshwari AV, Muro-Cacho CA, Pitcher JD October 2007 "Pigmented villonodular bursitis/diffuse giant cell tumor of the pes anserine bursa: a report of two cases and review of literature" Knee 14 5: 402–7 PMID 17669658 doi:101016/jknee200706004 
  4. ^ Murphey MD, Rhee JH, Lewis RB, Fanburg-Smith JC, Flemming DJ, Walker EA 2008 "Pigmented villonodular synovitis: radiologic-pathologic correlation" Radiographics 28 5: 1493–518 PMID 18794322 doi:101148/rg285085134 

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Villonodular synovitis

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