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tinidazole, tinidazole 500mg
Tinidazole is an anti-parasitic drug used against protozoan infections It is widely known throughout Europe and the developing world as a treatment for a variety of amoebic and parasitic infections It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class

Tinidazole is marketed by Mission Pharmacal under the brand name Tindamax, by Pfizer under the names Fasigyn and Simplotan, and in some Asian countries as Sporinex


  • 1 Uses
  • 2 Side effects
  • 3 Half-life
  • 4 References
  • 5 External links


A large body of clinical data exists to support use of tinidazole for infections from amoebae, giardia, and trichomonas, just like metronidazole Tinidazole may be a therapeutic alternative in the setting of metronidazole tolerance Tinidazole may also be used to treat a variety of other bacterial infections eg, as part of combination therapy for Helicobacter pylori eradication protocols

Side effects

Drinking alcohol while taking tinidazole causes an unpleasant disulfiram-like reaction, which includes nausea, vomiting, headache, increased blood pressure, flushing, and shortness of breath


Elimination half-life is 132 ± 14 hours Plasma half-life is 12 to 14 hours


  1. ^ Ebel, K, Koehler, H, Gamer, A O, & Jäckh, R “Imidazole and Derivatives” In Ullmann’s Encyclopedia of Industrial Chemistry; 2002 Wiley-VCH, doi:101002/14356007a13_661
  2. ^ Edwards, David I "Nitroimidazole drugs - action and resistance mechanisms I Mechanism of action" Journal of Antimicrobial Chemotherapy 1993, volume 31, pp 9-20 doi:101093/jac/3119

External links

  • MedlinePlus Drug Information: Tinidazole
  • Drug Bank Facts on Tinidazole

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Tinidazole Information about


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