Wed . 19 Jun 2019

Timeline of antibiotics

pictures of antibiotics, timeline of antibiotics
This is the timeline of antimicrobial anti-infective therapy The years show when a given drug was released onto the pharmaceutical market This is not a timeline of the development of the antibiotics themselves

  • 1911 – Arsphenamine aka Salvarsan
  • 1912 – Neosalvarsan
  • 1935 – Prontosil an oral precursor to sulfanilimide, the first sulfonamide
  • 1936 – Sulfanilimide
  • 1938 – Sulfapyridine M&B 693
  • 1939 – sulfacetamide
  • 1940 – sulfamethizole
  • 1942 – benzylpenicillin, the first penicillin
  • 1942 – gramicidin S, the first peptide antibiotic
  • 1942 – sulfadimidine
  • 1943 – sulfamerazine
  • 1944 – streptomycin, the first aminoglycoside
  • 1947 – sulfadiazine
  • 1948 – chlortetracycline, the first tetracycline
  • 1949 – chloramphenicol, the first amphenicol
  • 1949 – neomycin
  • 1950 – oxytetracycline
  • 1950 – penicillin G procaine
  • 1952 – erythromycin, the first macrolide
  • 1954 – benzathine penicillin
  • 1955 – spiramycin
  • 1955 – tetracycline
  • 1955 – thiamphenicol
  • 1955 – vancomycin, the first glycopeptide
  • 1956 – phenoxymethylpenicillin
  • 1958 – colistin, the first polymyxin
  • 1958 – demeclocycline
  • 1959 – virginiamycin
  • 1960 – methicillin
  • 1960 – metronidazole, the first nitroimidazole
  • 1961 – ampicillin
  • 1961 – spectinomycin
  • 1961 – sulfamethoxazole
  • 1961 – trimethoprim, the first dihydrofolate reductase inhibitor
  • 1962 – cloxacillin
  • 1962 – fusidic acid
  • 1963 – fusafungine
  • 1963 – lymecycline
  • 1964 – gentamicin
  • 1964 – cefalotin, the first cephalosporin
  • 1966 – doxycycline
  • 1967 – carbenicillin
  • 1967 – rifampicin
  • 1967 – nalidixic acid, the first quinolone
  • 1968 – clindamycin, the second lincosamide
  • 1970 – cefalexin
  • 1971 – cefazolin
  • 1971 – pivampicillin
  • 1971 – tinidazole
  • 1972 – amoxicillin
  • 1972 – cefradine
  • 1972 – minocycline
  • 1972 – pristinamycin
  • 1973 – fosfomycin
  • 1974 – talampicillin
  • 1975 – tobramycin
  • 1975 – bacampicillin
  • 1975 – ticarcillin
  • 1976 – amikacin
  • 1977 – azlocillin
  • 1977 – cefadroxil
  • 1977 – cefamandole
  • 1977 – cefoxitin
  • 1977 – cefuroxime
  • 1977 – mezlocillin
  • 1977 – pivmecillinam

From 1978

  • 1979 – cefaclor
  • 1980 – cefmetazole
  • 1980 – cefotaxime
  • 1980 – cefsulodin
  • 1980 – piperacillin
  • 1981 – co-amoxiclav amoxicillin/clavulanic acid
  • 1981 – cefoperazone
  • 1981 – cefotiam
  • 1981 – cefsulodin
  • 1981 – latamoxef
  • 1981 – netilmicin
  • 1982 – ceftriaxone
  • 1982 – micronomicin
  • 1983 – cefmenoxime
  • 1983 – ceftazidime
  • 1983 – ceftizoxime
  • 1983 – norfloxacin
  • 1984 – cefonicid
  • 1984 – cefotetan
  • 1984 – temocillin
  • 1985 – cefpiramide
  • 1985 – imipenem/cilastatin, the first carbapenem
  • 1985 – ofloxacin
  • 1986 – mupirocin
  • 1986 – aztreonam
  • 1986 – cefoperazone/sulbactam
  • 1986 – co-ticarclav ticarcillin/clavulanic acid
  • 1987 – ampicillin/sulbactam
  • 1987 – cefixime
  • 1987 – roxithromycin
  • 1987 – sultamicillin
  • 1987 – ciprofloxacin, the first 2nd-gen fluoroquinolone
  • 1987 – rifaximin, the first ansamycin
  • 1988 – azithromycin
  • 1988 – flomoxef
  • 1988 – isepamycin
  • 1988 – midecamycin
  • 1988 – rifapentine
  • 1988 – teicoplanin
  • 1989 – cefpodoxime
  • 1989 – enrofloxacin
  • 1989 – lomefloxacin
  • 1989 – moxifloxacin
  • 1990 – arbekacin
  • 1990 – cefozidime
  • 1990 – clarithromycin
  • 1991 – cefdinir
  • 1992 – cefetamet
  • 1992 – cefpirome
  • 1992 – cefprozil
  • 1992 – ceftibuten
  • 1992 – fleroxacin
  • 1992 – loracarbef
  • 1992 – piperacillin/tazobactam
  • 1992 – rufloxacin
  • 1993 – brodimoprim
  • 1993 – dirithromycin
  • 1993 – levofloxacin
  • 1993 – nadifloxacin
  • 1993 – panipenem/betamipron
  • 1993 – sparfloxacin
  • 1994 – cefepime
  • 1996 – meropenem
  • 1999 – quinupristin/dalfopristin
  • 2000 – linezolid, the first oxazolidinone
  • 2001 – telithromycin, the first ketolide
  • 2003 – daptomycin
  • 2005 – tigecycline, the first glycylcycline
  • 2005 – doripenem
  • 2009 – telavancin, the first Lipoglycopeptide
  • 2010 – ceftaroline
  • 2011 – fidaxomicin
  • 2012 – bedaquiline
  • 2013 – telavancin
  • 2014 – tedizolid
  • 2014 – dalbavancin
  • 2014 – ceftolozane/tazobactam
  • 2015 – ceftazidime/avibactam
  • 2018 – malacidins

See also

  • Timeline of medicine and medical technology
  • List of antibiotics, grouped by class

References

  1. ^ Sepkowitz, Kent A Jul 28, 2011 "One Hundred Years of Salvarsan" New England Journal of Medicine 365 4: 291–293 doi:101056/NEJMp1105345 PMID 21793743 
  2. ^ a b c Powers, J H November 2004 "Antimicrobial drug development – the past, the present, and the future" Clinical Microbiology and Infection 10 s4: 23–31 doi:101111/j1465-069120041007x PMID 15522037 

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Timeline of antibiotics


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    29.10.2014


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