Tue . 19 Oct 2019
TR | RU | UK | KK | BE |

Steroid diabetes

steroid diabetes, steroid diabetes treatment
Steroid diabetes also "steroid-induced diabetes" is a medical term referring to prolonged hyperglycemia due to glucocorticoid therapy for another medical condition It is usually, but not always, a transient condition


  • 1 Medical conditions
  • 2 Insulin
  • 3 Criteria
  • 4 Treatment
  • 5 Diagnosis
  • 6 General references

Medical conditions

The most common glucocorticoids which cause steroid diabetes are prednisolone and dexamethasone given systemically in "pharmacologic doses" for days or weeks Typical medical conditions in which steroid diabetes arises during high-dose glucocorticoid treatment include severe asthma, organ transplantation, cystic fibrosis, inflammatory bowel disease, and induction chemotherapy for leukemia or other cancers


Glucocorticoids oppose insulin action and stimulate gluconeogenesis, especially in the liver, resulting in a net increase in hepatic glucose output Most people can produce enough extra insulin to compensate for this effect and maintain normal glucose levels, but those who cannot develop steroid diabetes


The diagnostic criteria for steroid diabetes are those of diabetes fasting glucoses persistently above 125 mg/dl 7 mM or random levels above 200 mg/dl 11 mM occurring in the context of high-dose glucocorticoid therapy Insulin levels are usually detectable, and sometimes elevated, but inadequate to control the glucose In extreme cases the hyperglycemia may be severe enough to cause nonketotic hyperosmolar coma


Treatment depends on the severity of the hyperglycemia and the estimated duration of the steroid treatment Mild hyperglycemia in an immunocompetent patient may not require treatment if the steroids will be discontinued in a week or two Moderate hyperglycemia carries an increased risk of infection, especially fungal, and especially in people with other risk factors such as immunocompromise or central intravenous lines Insulin is the most common treatment


Steroid diabetes must be distinguished from stress hyperglycemia, hyperglycemia due to excessive intravenous glucose, or new-onset diabetes of another type Because it is not unusual for steroid treatment to precipitate type 1 or type 2 diabetes in a person who is already in the process of developing it, it is not always possible to determine whether apparent steroid diabetes will be permanent or will go away when the steroids are finished More commonly undiagnosed cases of type 2 diabetes are brought to clinical attention with corticosteroid treatment because subclinical hyperglycemia worsens and becomes symptomatic Generally, steroid diabetes without preexisting type 2 diabetes will resolve upon termination of corticosteroid administration

Steroid diabetes does not occur with other steroid hormones, such as anabolic steroids or sex steroids because these other categories of steroids have actually shown to have positive effects on glucose metabolism

General references

  • Steroid-Induced Diabetes Mellitus and Related Risk Factors in Patients With Neurologic Disease - MedScape

steroid diabetes, steroid diabetes and trying to gain weight, steroid diabetes is type 1 or 2, steroid diabetes is type 1 or 2 errors, steroid diabetes mechanism, steroid diabetes mellitus, steroid diabetes symptoms, steroid diabetes treatment

Steroid diabetes Information about

Steroid diabetes

  • user icon

    Steroid diabetes beatiful post thanks!


Steroid diabetes
Steroid diabetes
Steroid diabetes viewing the topic.
Steroid diabetes what, Steroid diabetes who, Steroid diabetes explanation

There are excerpts from wikipedia on this article and video

Random Posts

B♭ (musical note)

B♭ (musical note)

B♭ B-flat; also called si bémol is the eleventh step of the Western chromatic scale starting from C ...
Fourth dimension in art

Fourth dimension in art

New possibilities opened up by the concept of four-dimensional space and difficulties involved in tr...
Holt Renfrew

Holt Renfrew

Holt, Renfrew & Co, Limited, commonly known as Holt Renfrew or Holt's,1 is a chain of high-end C...
Later Silla

Later Silla

Later Silla 668–935, Hangul: 후신라; Hanja: 後新羅; RR: Hushila, Korean pronunciation: ...