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Squamous metaplasia

squamous metaplasia, squamous metaplasia pap smear
Squamous metaplasia is a benign non-cancerous change metaplasia of surfacing lining cells epithelium to a squamous morphology


  • 1 Location
    • 11 Uterine cervix
  • 2 Significance
  • 3 See also
  • 4 References


Common sites for squamous metaplasia include the bladder and cervix Smokers often exhibit squamous metaplasia in the linings of their airways These changes don't signify a specific disease, but rather usually represent the body's response to stress or irritation Vitamin A deficiency or overdose can also lead to squamous metaplasia

Uterine cervix

In regard to the cervix, squamous metaplasia can sometimes be found in the endocervix, as it is composed of simple columnar epithelium, whereas the ectocervix is composed of stratified squamous non-keratinized epithelium


Squamous metaplasia may be seen in the context of benign lesions eg atypical polypoid adenomyoma, chronic irritation or cancer eg endometrioid endometrial carcinoma

See also

  • Metaplasia
  • Dysplasia
  • Barrett esophagus - a columnar cell metaplasia of squamous epithelium
  • Subareolar abscess


  1. ^ Goralczyk, R 2009 "ß-Carotene and Lung Cancer in Smokers: Review of Hypotheses and Status of Research" Nutrition and Cancer 61 6: 767–774 doi:101080/01635580903285155 PMID 20155614 
  2. ^ Kumar, Vinay; Abbas, Abul K; Fausto, Nelson; & Mitchell, Richard N 2007 Robbins Basic Pathology 8th ed Saunders Elsevier pp 716-720 ISBN 978-1-4160-2973-1

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Squamous metaplasia

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