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Somnology

somnology definition, somnology sleep scanner
Somnology is the scientific study of sleep It includes clinical study and treatment of sleep disorders and irregularities Sleep medicine is a subset of somnology

Contents

  • 1 History
  • 2 The International Classification of Sleep Disorders
  • 3 Diagnostic tools
    • 31 Sleep diaries
    • 32 Sleep questionnaires
    • 33 Actigraphy
    • 34 Physical examination
    • 35 Polysomnography
      • 351 Airflow measurements
      • 352 Oxygenation and ventilation measurements
    • 36 Snoring
    • 37 Multiple Sleep Latency Test
    • 38 Maintenance of Wakefulness Test
  • 4 Treatments
    • 41 Behavioral treatments
    • 42 Mechanical treatments
    • 43 Pharmacological treatments
  • 5 See also
  • 6 References

Historyedit

Sleep and sleep disorders have been recorded and treated in ancient times; Hippocrates mentions disturbances of sleep in his writings, ancient Egypt used opium as a treatment for insomnia, and some mention how dreams reflect the state of the body However, despite these early references to sleep and its disorders, serious studies on sleep did not truly begin until the invention of the electroencephalogram EEG in 19291

After the invention of the EEG, the stages of sleep were determined in 1936 by Harvey and Loomis, the first descriptions of delta and theta waves were made by Walter and Dovey, and REM sleep was discovered in 1953 Sleep apnea was identified in 19652 In 1970, the first clinical sleep laboratory was developed at Stanford3 The first actigraphy device was made in 1978 by Krupke, and continuous positive airway pressure therapy and uvulopalatopharyngoplasty were created in 1981

The Examination Committee of the Association of Sleep Disorders Centers, which is now the American Academy of Sleep Medicine, was established in 1978 and administered the sleep administrationclarification needed test until 1990 In 1989, the American Board of Sleep Medicine was created to administer the tests and eventually assumed all the duties of the Examination committee in 1991 In the United States, the American Board of Sleep Medicine grants certification for sleep medicine to both physicians and non-physicians However, the board does not allow one to practice sleep medicine without a medical license4

The International Classification of Sleep Disordersedit

Created in 1990 by the American Academy of Sleep Medicine with assistance from European Sleep Research Society, the Japanese Society of Sleep Research, and the Latin American Sleep Society, the International Classification of Sleep Disorders is the primary reference for scientists and diagnosticians Sleep disorders are separated into four distinct categories: parasomnias; dyssomnias; sleep disorders associated with mental, neurological, or other medical conditions; and sleep disorders that do not have enough data available to be counted as definitive sleep disorders The ICSD has created a comprehensive description for each sleep disorder with the following information5

  • Synonyms and Key Words – This section describes the terms and phrases used to describe the disorder and also includes an explanation on the preferred name of the disorder when appropriate
  • Essential Features – This section describes the main symptoms and features of the disorder
  • Associated Features – This section describes the features that appear often but not always present Furthermore, complications that are caused directly by the disorder are listed here
  • Course – This section describes the clinical course and the outcome of an untreated disorder
  • Predisposing Factors – This section describes internal and external factors that increase the chances of a patient developing the sleep disorder
  • Prevalence – This section, if known, describes the proportion of people who have or had this disorder
  • Age of Onset – This section describes the age range when the clinical features first appear
  • Sex Ratio – This section describes the relative frequency that the disorder is diagnosed in each sex
  • Familial Pattern – This section describes whether the disorder is found among family members
  • Pathology – This section describes the microscopic pathologic features of the disorder If this is not known, the pathology of the disorder is described instead
  • Complications – This section describes any possible disorders or complications that can occur because of the disease
  • Polysomnographic Features – This section describes how the disorder appears under a polysomnograph
  • Other Laboratory Features - This section describes other laboratory test such as blood tests and brain imaging
  • Differential Diagnosis – This section describes disorders with similar symptoms
  • Diagnostic Criteria – This section has the criteria that can make a clear cut diagnosis
  • Minimal Criteria – This section is used for general clinical practice and is used to make a provisional diagnosis
  • Severity Criteria – This section has a three-part classification into “mild,” “moderate,” and “severe” and also describes the criteria for the severity
  • Duration Criteria – This section allows a clinician to determine how long a disorder has been present and separates the durations into “acute,” “subacute,” and “chronic
  • Bibliography – This section contains the references

Diagnostic toolsedit

Somnologists employ various diagnostic tools to determine the nature of a sleep disorder or irregularity Some of these tools can be subjective such as the sleep diaries or the sleep questionnaire Other diagnostic tools are used while the patient is asleep such as the polysomnograph and actigraphy

Sleep diariesedit

A sleep diary is a daily log made by the patient that contains information about the quality and quantity of sleep The information includes sleep onset time, sleep latency, number of awakenings in a night, time in bed, daytime napping, sleep quality assessment, use of hypnotic agents, use of alcohol and cigarettes, and unusual events which may influence a person’s sleep Such a log is usually made for one or two weeks before visiting a somnologist The sleep diary may be used in conjunction with actigraphy

Sleep questionnairesedit

Sleep questionnaires help determine the presence of a sleep disorder by asking a patient to fill out a questionnaire about a certain aspect of their sleep such as daytime sleepiness These questionnaires include the Epworth Sleepiness Scale, the Stanford Sleepiness Scale, and the Sleep Timing Questionnaire

The Epworth Sleepiness Scale measures general sleep propensity and asks the patient to rate their chances of dozing off in eight different situations The Stanford Sleepiness Scale asks the patient to note their perception of sleepiness by using a seven-point test The Sleep Timing Questionnaire is a 10-minute self-administration test that can be used in place of a 2-week sleep diary The questionnaire can be a valid determinate of sleep parameters such as bed time, wake time, sleep latency, and wake after sleep onset6

Actigraphyedit

Actigraphy can assess sleep/wake patterns without confining one to the laboratory The monitors are small, wrist-worn movement monitors that can record activity for up to several weeks Sleep and wakefulness are determined by using an algorithm that analyzes the movement of the patient and the input of bed and wake times from a sleep diary

Physical examinationedit

A physical examination can determine the presence of other medical conditions that can cause a sleep disorder

Polysomnographyedit

Polysomnography involves the continuous monitoring of multiple physiological variables during sleep These variables include electroencephalography, electrooculography, electromyography, and electrocardiography as well as airflow, oxygenation, and ventilation measurements Electroencephalography measures the voltage activity of neuronal somas and dendrites within the cortex, electro-oculography measures the potential between cornea and retina, electromyography is used to identify REM sleep by measuring the electrical potential of skeletal muscle, and electrocardiography measures cardiac rate and rhythm It is important to point out that EEG, in particular, always refers to a collective of neurons firing as EEG equipment is not sensitive enough to measure a single neuron

Airflow measurementsedit

Airflow measurement can be used to indirectly determine the presence of an apnea; measurements are taken by pneumotachography, nasal pressure, thermal sensors, and expired carbon dioxide Pneumotachography measures the difference in pressure between inhalation and exhalation, nasal pressure can help determine the presence of airflow similar to pneumotachography, thermal sensors detect the difference in temperature between inhaled and exhaled air, and expired carbon dioxide monitoring detect the difference in carbon dioxide between inhaled and exhaled air

Oxygenation and ventilation measurementsedit

The monitoring of oxygenation and ventilation is important in the assessment of sleep-related breathing disorders However, because oxygen values can change often during the course of sleep, repeated measurements must be taken to ensure accuracy The direct measurements of arterial oxygen tension only offer a static glimpse, and repeated measurements from invasive procedures such as sampling arterial blood for oxygen will disturb the patient’s sleep; therefore, noninvasive methods are preferred such as pulse oximetry, transcutaneous oxygen monitoring, transcutaneous carbon dioxide, and pulse transit time

Pulse oximetry measures the oxygenation in peripheral capillaries such as the fingers; however, an article written by Bohning states that pulse oximetry may be imprecise for use in diagnosing obstructive sleep-apnea, due to the differences in signal processing in the devices7

Transcutaneous oxygen and carbon dioxide monitoring measures the oxygen and carbon dioxide tension on the skin surface respectively, and the pulse transit time measures the transmission time of an arterial pulse transit wave For the lattermost, pulse transit time increases when one is aroused from sleep, making it useful in determining sleep apnea

Snoringedit

Snoring can be detected by a microphone and may be a symptom of obstructive sleep-apnea89

Multiple Sleep Latency Testedit

The Multiple Sleep Latency Test MSLT measures a person’s physiological tendency to fall asleep during a quiet period in terms of sleep latency, the amount of time it takes for someone An MSLT is normally performed after a nocturnal polysomnography to ensure both an adequate duration of sleep and to exclude other sleep disorders10

Maintenance of Wakefulness Testedit

The Maintenance of Wakefulness Test MWT measures a person’s ability to stay awake for a certain period of time, essentially measuring the time one can stay awake during the day The test isolates a person from factors that can influence sleep such as temperature, light, and noise Furthermore, the patient is also highly suggested to not take any hypnotics, drink alcohol, or smoke before or during the test After allowing the patient to lie down on the bed, the time between lying down and falling asleep is measured and used to determine one’s daytime sleepiness

Treatmentsedit

Though somnology does not necessarily mean sleep medicine, somnologists can use behavioral, mechanical, or pharmacological means to correct a sleep disorder

Behavioral treatmentsedit

Behavioral treatments tend to be the most prescribed and the most cost-efficient of all treatments; these treatments include exercise, cognitive behavioral therapy, relaxation therapy, meditation, and improving sleep hygiene11 Improving sleep hygiene includes making the patient sleep regularly, discourage the patient from taking daytime naps, or suggesting they sleep in a different position

Mechanical treatmentsedit

Mechanical treatments are primarily used to reduce or eliminate snoring and can be either invasive or non-invasive Surgical procedures for treating snoring include palatal stiffening techniques, uvulopalatopharyngoplasty and uvulectomy while non-invasive procedures include continuous positive airway pressure, mandibular advancement splints, and tongue-retaining devices12

Pharmacological treatmentsedit

Pharmacological treatments are used to chemically treat sleep disturbances such as insomnia or excessive daytime sleepiness The kinds of drugs used to treat sleep disorders include: anticonvulsants, anti-narcoleptics, anti-Parkinsonian drugs, benzodiazepines, non-benzodiazepine hypnotics, and opiates as well as the hormone melatonin and melatonin receptor stimulators Anticonvulsants, opiates, and anti-Parkinsonian drugs are often used to treat restless legs syndrome Furthermore, melatonin, benzodiazepines hypnotics, and non-benzodiazepine hypnotics may be used to treat insomnia Finally, anti-narcoleptics help treat narcolepsy and excessive daytime sleepiness

Of particular interest are the benzodiazepine drugs which reduce insomnia by increasing the efficiency of GABA GABA decreases the excitability of neurons by increasing the firing threshold Benzodiazepine causes the GABA receptor to better bind to GABA, allowing the medication to induce sleep13

Generally, these treatments are given after the behavioral treatment has failed Drugs such as tranquilizers, though they may work well in treating insomnia, have a risk of abuse which is why these treatments are not the first resort Some sleep disorders such as narcolepsy do require pharmacological treatment

See alsoedit

  • Sleep disorder
  • Sleep medicine
  • Snoring

Referencesedit

  1. ^ D Todman: A History Of Sleep Medicine The Internet Journal of Neurology Volume 9 2008
  2. ^ Bradley DT Respritory Sleep Medicine American Journal of Respiratory and Critical Care Medicine 2008 Vol 117
  3. ^ Bowman TJ Review of Sleep Medicine Burlington, MA: Butterworth-Heinemann, 2002
  4. ^ "American Board of Sleep Medicine" 
  5. ^ "The International Classification of Sleep Disorders, Revised: Diagnostic and Coding Manual" 2001 edition, ISBN 0-9657220-1-5, PDF-complete, Library of Congress Catalog No 97-71405 http://wwwesstorg/adds/ICSDpdf
  6. ^ R Tremaine, J Dorrian and S Blunden Measuring Sleep Habits using the Sleep Timing Questionnaire: A Validation Study for School-Age Children Sleep and Biological Rhythms 2010 Volume 8
  7. ^ Bohning, N , Schultheiss, B, Eilers, S, Penzel, T, Bohning, W, et al 2010 Comparability of Pulse Oximeters Used in Sleep Medicine for the Screening of OSA Physiological Measurement, 317, 875-888
  8. ^ Migita, M, Gocho, Y, Ueda, T, Saigusa, H, & Fukunaga, Y 2010 An 8-year-old Girl with a Recurrence of Obstructive Sleep Apnee Syndrome Caused by Hypertrophy of Tubal Tonsils 4 Years After Adenotonsillectomy Journal of Nippon Medical School, 775, 265-268
  9. ^ http://wwwforgetsnoringorg/forget-snoring-real/
  10. ^ J Murray A new perspective on sleepiness Sleep and Biological Rhythms 2010; 8: 170–179
  11. ^ Roehrs, T 2009 Does Effective Management of Sleep Disorders Improve Pain Symptoms Drugs, 69, 5-11
  12. ^ Main, C, Liu, Z, Welch, K, Weiner, G, Jones, S, et al 2009 Surgical Procedures and Non-surgical Devices for the Management of Non-apnoeic Snoring: A Systematic Review of Clinical Effects and Associated Treatment Costs Clinical Otolaryngology, 343, 240-244
  13. ^ Sangameswaran, L , & Blas, A 1985 Demonstration of Benzodiazepine-Like Molecules in the Mammalian Brain with a Monoclonal Antibody to Benzodiazepines Proceedings of the National Academy of Sciences of the United States of America, 8216, 5560-5564

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    29.10.2014


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