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Raja M. Flores

raja m flores md, dr. raja m. flores
Raja Michael Flores, MD, is an American thoracic surgeon, currently Chief of the Division of Thoracic Surgery at Mount Sinai Hospital and Ames Professor of Cardiothoracic Surgery at the Icahn School of Medicine at Mount Sinai, both in New York City1

Contents

  • 1 Biography
  • 2 Research
  • 3 Publications
  • 4 References
  • 5 External links

Biographyedit

Flores received a BA in biochemistry from New York University in 1988 and his MD from Albert Einstein College of Medicine in 1992 His internship 1992–1993 and residency 1993–1997 at Columbia-Presbyterian Medial Center were followed by a Thoracic Oncology Clinical Research Fellowship 1997–1998 in Intraoperative Chemotherapy, Mesothelioma and Lung Cancer at Brigham and Women's Hospital/Dana-Farber Cancer Institute, and a Cardiothoracic Surgery Residency 1998-2000 at Harvard Medical School, both in Boston, Massachusetts23

Flores is currently an editorial board member for the World Journal of Gastrointestinal Surgery, the World Journal of Gastrointestinal Edoscopy and the World Journal of Respirology He is a reviewer for 13 other journals including Head & Neck, the Journal of Thoracic and Cardiovascular Surgery, the Journal of Thoracic Oncology and the Journal of Clinical Oncology Memberships include the American College of Chest Physicians, the American College of Surgeons Oncology Group and the American Society of Clinical Oncology4

Researchedit

Flores' research has significantly impacted the surgical management of pleural mesothelioma by demonstrating that partial pleural membrane removal is as effective a treatment as lung removal5 He was instrumental in creating VATS lobectomy as the standard in the surgical treatment of lung cancer678 and is considered a pioneer in the use of intraoperative chemotherapy for mesothelioma9

Flores is the author of more than 60 book chapters, reviews, monographs and abstracts and more than 150 publications He serves as a reviewer for 13 journals and has been an editorial board member on four journals He is the principal investigator on five clinical trials and has been ranked in the top 1% in his field by US News & World Report510

Flores areas of interest include lung cancer screening, thoracoscopy, VATS lobectomy, extrapleural pneumonectomy for mesothelioma, asbestos, tracheal stenosis, carinal surgery and esophageal cancer surgery11 He is the principal investigator for a clinical trial of neoadjuvant gemcitabine and cisplatin followed by extrapleural pneumonectomy and high-dose radiation4

Other research includes:

Role Title Affiliation
Co-Principal Investigator Extrapleural Pneumonectomy Followed by Intrathoracic/Intraperitoneal Heated Cisplatin and Intravenous Sodium Thiosulfate in the Multimodality Treatment of Malignant Pleural Mesothelioma: A Phase I Study Brigham & Women's Hospital
Principal Investigator Randomized, Prospective Trial of Mediastinal LN Sampling Vs Complete Lymphadenectomy During Conduct of Pulmonary Resection in Patients with N0 and N1 less than hilar non-small cell carcinoma ACOSOG Z0030 Memorial Sloan-Kettering Cancer Center
Principal Investigator A Randomized Phase III Trial Surgery Alone or Surgery Plus Preoperative

Paclitaxel/Carboplatin in Clinical Stage IB T2N0, II T1-2N1, T3N0 and selected IIIA None Small Cell Lung Cancer NSCLC – RTOGL-0015 S9900

Memorial Sloan-Kettering Cancer Center
Principal Investigator The Role of Laparoscopic Staging in Patients with Resectable Gastroesophageal Junction Carcinomas Memorial Sloan-Kettering Cancer Center
Principal Investigator A Phase II Trial of Induction Chemotherapy, Surgical Resection and Adjuvant External Beam Radiation for Locally Advanced Malignant Pleural Mesothelioma Memorial Sloan-Kettering Cancer Center
Principal Investigator A Phase II Trial of Induction Chemotherapy, Surgical Resection, and Adjuvant External Beam Radiation for Locally Advanced Malignant Pleural Mesothelioma Lilly Research Laboratories

Publicationsedit

Partial list:

  • Flores, RM; Ihekweazu, UN; Rizk, NP; Dycoco, J; Bains, MS; Downey, RJ; Adusumilli, PS Jan 2011 "Patterns of recurrence and incidence of second primary tumors after lobectomy by VATS versus thoracotomy for lung cancer" J Thorac Cardiovasc Surg 141 1: 59–64 PMID 21055770 doi:101016/jjtcvs201008062 
  • Kaufman, AJ; Flores, RM Jun 2011 "Surgical treatment of malignant pleural mesothelioma" Curr Treat Options Oncol 12 2: 201–16 PMID 21465419 doi:101007/s11864-011-0154-4 
  • Flores, RM Feb 2011 "Reply to difference in outcome in the transection of the pulmonary artery and vein" J Thorac Cardiovasc Surg 141 2: 597–8 PMID 21241869 doi:101016/jjtcvs201010008 
  • Rai, AJ; Flores, RM Jan 2011 "Association of malignant mesothelioma and asbestos related conditions with ovarian cancer: shared biomarkers and a possible etiological link" Clin Chem Lab Med 49 1: 5–7 PMID 21158701 doi:101515/CCLM2011027 
  • Flores, RM; Ihekweazu, UN; Rizk, N; Dycoco, J; Bains, MS; Downey, RJ; Adusumilli, P; Finley, DJ; Huang, J; Rusch, VW; Sarkaria, I; Park, B Jan 2011 "Patterns of recurrence and incidence of second primary tumors after lobectomy by means of video-assisted thoracoscopic surgery VATS versus thoracotomy for lung cancer" J Thorac Cardiovasc Surg 141 1: 59–64 PMID 21055770 doi:101016/jjtcvs201008062 
  • Flores, RM; Riedel, E; Donington, JS; Alago, W; Ihekweazu, U; Krug, L; Rosenzweig, K; Adusumilli, PS; Carbone, M; Pass, HI Oct 2010 "Frequency of use and predictors of cancer-directed surgery in the management of malignant pleural mesothelioma in a community-based Surveillance, Epidemiology, and End Results SEER population" J Thorac Oncol 5 10: 1649–54 PMID 20871264 doi:101097/JTO0b013e3181f1903e 
  • Ihekweazu, UN; Ludwig, E; Flores, RM Aug 2010 "PillCam in gastric conduit after Ivor Lewis esophagectomy" Ann Thorac Surg 90 2: 673 PMID 20667385 doi:101016/jathoracsur200910042 
  • Abbey, AM; Flores, RM Aug 2010 "Spontaneous resolution of a pericardial cyst" Ann Thorac Cardiovasc Surg 16 1: 55–6 PMID 20190713 
  • Rai, AJ; Flores, RM; Mathew, A; Gonzalez-Espinoza, R; Bott, M; Ladanyi, M; Rusch, V; Fleisher, M Feb 2010 "Soluble mesothelin related peptides SMRP and osteopontin as protein biomarkers for malignant mesothelioma: analytical validation of ELISA based assays and characterization at mRNA and protein levels" Clin Chem Lab Med 48 2: 271–8 PMID 20131968 doi:101515/CCLM2010066 
  • Flores, RM Feb 2010 "Invited commentary" Ann Thorac Surg 89 2: 396 PMID 20103307 doi:101016/jathoracsur200911040 
  • Blasberg, JD; Pass, HI; Goparaju, CM; Flores, RM; Lee, S; Donington, JS Feb 2010 "Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer" J Clin Oncol 28 6: 936–41 PMC 2834433  PMID 20085934 doi:101200/JCO2009255711 
  • Flores, RM Apr 2010 "Video-assisted thoracic surgery VATS lobectomy: focus on technique" World J Surg 34 4: 616–20 PMID 20082195 doi:101007/s00268-009-0340-8 
  • Blasberg, JD; Pass, HI; Goparaju, CMV; Flores, RM; Lee, S; Donington, JS Feb 2010 "Reduction of elevated plasma osteopontin levels with resection of non-small cell lung cancer" J Clin Oncol 28 6: 936–41 PMC 2834433  PMID 20085934 doi:101200/JCO2009255711 
  • Flores, RM Apr 2010 "Video-assisted thoracic surgery VATS lobectomy: focus on technique" World J Surg 34 4: 616–20 PMID 20082195 doi:101007/s00268-009-0340-8 
  • Flores, RM; Riedel, E; Donington, JS; Alago, W; Ihekweazu, U; Krug, L; Rosenzweig, K; Adusumilli, PS; Carbone, M; Pass, HI Oct 2010 "Frequency of use and predictors of cancer directed surgery in the management of malignant pleural mesothelioma in a community-based SEER population" J Thorac Oncol 5 10: 1649–1654 PMID 20871264 doi:101097/JTO0b013e3181f1903e 
  • Flores, RM Summer 2009 "Surgical options in malignant pleural mesothelioma: extrapleural pneumonectomy or pleurectomy/decortication" Semin Thorac Cardiovasc Surg 21 2: 149–53 PMID 19822286 doi:101053/jsemtcvs200906008 
  • Flores, RM; Park, BJ; Dycoco, J; Aronova, A; Hirth, Y; Rizk, NP; Bains, M; Downey, RJ; Rusch, VW 2009 "Lobectomy by video-assisted thoracic surgery VATS versus thoracotomy for lung cancer" J Thorac Cardiovasc Surg 138 1: 11–18 PMID 19577048 doi:101016/jjtcvs200903030 
  • Flores, RM; Park, BJ; Dycoco, J; Aronova, A; Hirth, Y; Rizk, NP; Bains, M; Downey, RJ; Rusch, VW Jul 2009 "Lobectomy by video-assisted thoracic surgery VATS versus thoracotomy for lung cancer" J Thorac Cardiovasc Surg 138 1: 11–8 PMID 19577048 doi:101016/jjtcvs200903030 
  • Flores RM, Pass HI, Seshan VE, Dycoco J, Zakowski M, Carbone M, Bains MS, Rusch VW "Extrapleural Pneumonectomy EPP versus Pleurectomy/Decortication P/D in the surgical management of malignant pleural mesothelioma MPM: Results in 663 patients J Thorac Cardiovasc Surg 2008 Mar; 1353:620-6, 626el-3 doi:101016/jjtcvs200710054 PMID 18329481
  • Garcia, A; Flores, RM 2008 "Surgical Management of tumors invading the superior vena cava" Ann Thorac Surg 85 6: 2144–6 PMID 18498851 doi:101016/jathoracsur200712027 
  • Flores, RM; Routledge, T; Venkatraman, E; Dycoco, J; Hirth, Y; Rusch, VW Sep 2008 "The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma MPM: implications for revision of the AJCC staging system" J Thorac Cardiovasc Surg 136 3: 605–610 PMID 18805259 doi:101016/jjtcvs200802069 
  • Garcia, A; Byrne, JG; Bueno, R; Flores, RM Dec 2008 "Aneurysm of the main pulmonary artery" Ann Thorac Cardiovasc Surg 14 6: 399–401 PMID 19131930 
  • Flores, RM; Zakowski, M; Venkatraman, E; Krug, L; Rosenzweig, K; Dycoco, J; Lee, C; Yeoh, C; Bains, M; Rusch, VW 2007 "Prognostic Factors in the Treatment of Malignant Pleural Mesothelioma MPM at a Large Tertiary Referral Center" J Thorac Oncol 2 10: 957–65 PMID 17909360 doi:101097/JTO0b013e31815608d9 
  • Flores, RM; Krug, LM; Rosenzweig, KE; Venkatraman, E; Vincent, A; Heelan, R; Akhurst, T; Rusch, VW May 2006 "Induction chemotherapy, extrapleural pneumonectomy, and postoperative high dose radiotherapy for locally advanced malignant pleural mesothelioma A phase II trial" J Thorac Oncol 1 4: 289–95 PMID 17409872 doi:101097/01243894-200605000-00004 
  • Flores, RM; Alam, N 2006 "Treatment of malignant pleural mesothelioma: pleurectomy with adjuvant therapy" Operative Techniques in Thor and Cardiovasc Surg 11 1: 57–74 doi:101053/joptechstcvs200602002 
  • Flores, RM; Akhurst, T; Gonen, M; Zakowski, M; Dycocco, J; Larsen, SM; Rusch, VW 2006 "Positron emission tomography predicts survival in malignant pleural mesothelioma" J Thorac Cardiovasc 132 4: 763–8 PMID 17000285 doi:101016/jjtcvs200603068 
  • Flores, RM; Su, W; Lal, D; Rusch, VW; LaQuaglia, MP 2006 "Extrapleural pneumonectomy in children" J Ped Surg 41 10: 1738–42 PMID 17011280 doi:101016/jjpedsurg200605063 
  • Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, DeCamp MM Jr, Swanson SJ, Bueno R, Lukanich JM, Baldini EH, Mentzer SJ "Resection margins, extrapleural nodal status, and cell type determine survival in trimodality therapy of malignant pleural mesothelioma MPM: Results in 183 patients Seventy-eighth meeting of the American Association of Thoracic Surgery 1998 Boston, MA PMID 9869758

Referencesedit

  1. ^ "Icahn School of Medicine at Mount Sinai - Raja M Flores" Retrieved November 1, 2011 
  2. ^ "Raja Flores, MD, Named Chief of Thoracic Surgery at The Mount Sinai Hospital" Retrieved November 1, 2011 
  3. ^ "Dr Raja M Flores - Sharecare" Retrieved November 1, 2011 
  4. ^ a b "mesotheliomaweborg" Retrieved November 1, 2011 
  5. ^ a b "Albert Einstein College of Medicine" Retrieved November 1, 2011 
  6. ^ "Mesothelioma Resource Online" Retrieved November 1, 2011 
  7. ^ "Society of Surgical Oncology" Retrieved November 1, 2011 
  8. ^ "BusinessWeek" Retrieved November 1, 2011 
  9. ^ "The ASCO Post" Retrieved November 1, 2011 
  10. ^ "US News & World Report - Top Doctors" Retrieved November 1, 2011 
  11. ^ "The Cardiothoracic Surgery Network" Retrieved November 1, 2011 

External linksedit

  • Mount Sinai Hospital homepage
  • Icahn School of Medicine at Mount Sinai homepage
  • YouTube – Dr Flores at the International Symposium on Malignant Mesothelioma, 2008
  • YouTube – Dr Flores at the Mesothelioma Symposium, 2009

dr. raja m. flores, raja m flores md, raja m. flores


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