Fri . 19 Apr 2019

Radezolid

radezolid wikipedia, radezolid fda approved
Radezolid INN, codenamed RX-1741 is a novel oxazolidinone antibiotic being developed by Melinta Therapeutics, Inc for the treatment of bacterial acne

References

  1. ^ Stearns, John August 1, 2016 "Melinta Therapeutics takes aim at deadly drug-resistant bacteria" Hartford Business Journal 

Further reading

  • Zhou J, Bhattacharjee A, Chen S, et al December 2008 "Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics" Bioorg Med Chem Lett 18 23: 6175–8 doi:101016/jbmcl200810011 PMID 18947996 
  • Skripkin E, McConnell TS, DeVito J, et al October 2008 "Rχ-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance" Antimicrob Agents Chemother 52 10: 3550–7 doi:101128/AAC01193-07 PMC 2565890  PMID 18663023 
  • Lawrence L, Danese P, DeVito J, Franceschi F, Sutcliffe J May 2008 "In vitro activities of the Rχ-01 oxazolidinones against hospital and community pathogens" Antimicrob Agents Chemother 52 5: 1653–62 doi:101128/AAC01383-07 PMC 2346622  PMID 18316525 
  • Hanselmann R, Job G, Johnson G, Lou R, Martynow JG, Reeve MM 2009 "Synthesis of an antibacterial compound containing a 1,4-substituted 1H-1,2,3-triazole- a scaleable alternative to the "click" reaction"" Organic Process Research and Development 14: 152–158 doi:101021/op900252a 
  • Franceschi F, Duffy EM March 2006 "Structure-based drug design meets the ribosome" Biochem Pharmacol 71 7: 1016–25 doi:101016/jbcp200512026 PMID 16443192 
  • Ohlsen K November 2009 "Novel antibiotics for the treatment of Staphylococcus aureus" Expert Rev Clin Pharmacol 2 6: 661–72 doi:101586/ecp0926 



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Radezolid


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    Radezolid beatiful post thanks!

    29.10.2014


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