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PHTPP


PHTPP is a synthetic, nonsteroidal, and highly selective antagonist of ERβ that is used in scientific research to study the function of this receptor It possesses 36-fold selectivity for ERβ over ERα, and is a silent antagonist of ERβ

See also

  • Propylpyrazoletriol PPT
  • Methylpiperidinopyrazole MPP
  • R,R-Tetrahydrochrysene R,R-THC
  • Diarylpropionitrile DPN
  • Prinaberel ERB-041
  • Liquiritigenin
  • Menerba
  • WAY-200070

References

  1. ^ Neurosteroids Frontiers E-books pp 95– ISBN 978-2-88919-078-2 
  2. ^ Cytoplasmic and Nuclear Receptors—Advances in Research and Application: 2012 Edition ScholarlyEditions 26 December 2012 pp 220– ISBN 978-1-4649-9741-9 
  3. ^ Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA 2004 "Pyrazolopyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity" J Med Chem 47 24: 5872–93 doi:101021/jm049631k PMID 15537344 




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