PHTPP is a synthetic, nonsteroidal, and highly selective antagonist of ERβ that is used in scientific research to study the function of this receptor It possesses 36-fold selectivity for ERβ over ERα, and is a silent antagonist of ERβ
- Propylpyrazoletriol PPT
- Methylpiperidinopyrazole MPP
- R,R-Tetrahydrochrysene R,R-THC
- Diarylpropionitrile DPN
- Prinaberel ERB-041
- ^ Neurosteroids Frontiers E-books pp 95– ISBN 978-2-88919-078-2
- ^ Cytoplasmic and Nuclear Receptors—Advances in Research and Application: 2012 Edition ScholarlyEditions 26 December 2012 pp 220– ISBN 978-1-4649-9741-9
- ^ Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA 2004 "Pyrazolopyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity" J Med Chem 47 24: 5872–93 doi:101021/jm049631k PMID 15537344
|See also Receptor/signaling modulators Estrogens and antiestrogens Androgen receptor modulators Progesterone receptor modulators List of estrogens|
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