Wed . 19 Apr 2019

Peptidoglycan glycosyltransferase

peptidoglycan glycosyltransferase and blood, peptidoglycan glycosyltransferases
In enzymology, a peptidoglycan glycosyltransferase EC 241129 is an enzyme that catalyzes the chemical reaction

n- diphosphoundecaprenol + GlcNAc-1->4-Mur2Acoyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala- diphosphoundecaprenol ⇌ n+1- diphosphoundecaprenol + undecaprenyl diphosphate

The 4 substrates of this enzyme are

  • n-,
  • diphosphoundecaprenol,
  • GlcNAc-1->4-Mur2Acoyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala-, and
  • diphosphoundecaprenol,

whereas its 3 products are

  • n+1-,
  • diphosphoundecaprenol, and
  • undecaprenyl diphosphate

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases The systematic name of this enzyme class is undecaprenyldiphospho-N-acetyl-D-glucosaminyl-1->4-N-acetyl-D-mu ramoylpentapeptide:undecaprenyldiphospho-N-acetyl-D-glucosaminyl- 1->4-N-acetyl-D-muramoylpentapeptide disaccharidetransferase Other names in common use include PG-II, bactoprenyldiphospho-N-acetylmuramoyl-N-acetyl-D-glucosaminyl-, pentapeptide:peptidoglycan, N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase, penicillin binding protein 3 or 1B, and peptidoglycan transglycosylase This enzyme participates in peptidoglycan biosynthesis

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2BG1, 2UWX, and 2UWY

References

  • Taku A, Stuckey M, Fan DP 1982 "Purification of the peptidoglycan transglycosylase of Bacillus megaterium" J Biol Chem 257 9: 5018–22 PMID 6802846 
  • Goffin C, Ghuysen JM 1998 "Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs" Microbiol Mol Biol Rev 62 4: 1079–93 PMC 98940  PMID 9841666 
  • van Heijenoort J 2001 "Formation of the glycan chains in the synthesis of bacterial peptidoglycan" Glycobiology 11 3: 25R–36R doi:101093/glycob/11325R PMID 11320055 
  • Molecular and Cellular Biology portal


peptidoglycan glycosyltransferase and blood, peptidoglycan glycosyltransferase bacteria, peptidoglycan glycosyltransferase function, peptidoglycan glycosyltransferases


Peptidoglycan glycosyltransferase Information about

Peptidoglycan glycosyltransferase


  • user icon

    Peptidoglycan glycosyltransferase beatiful post thanks!

    29.10.2014


Peptidoglycan glycosyltransferase
Peptidoglycan glycosyltransferase
Peptidoglycan glycosyltransferase viewing the topic.
Peptidoglycan glycosyltransferase what, Peptidoglycan glycosyltransferase who, Peptidoglycan glycosyltransferase explanation

There are excerpts from wikipedia on this article and video

Random Posts

La Porte, Indiana

La Porte, Indiana

La Porte French for "The Door" is a city in LaPorte County, Indiana, United States, of which it is t...
Fernando Montes de Oca Fencing Hall

Fernando Montes de Oca Fencing Hall

The Fernando Montes de Oca Fencing Hall is an indoor sports venue located in the Magdalena Mixhuca S...
My Everything (The Grace song)

My Everything (The Grace song)

"My Everything" was Grace's 3rd single under the SM Entertainment, released on November 6, 2006 Unli...
Turkish Straits

Turkish Straits

The Turkish Straits Turkish: Türk Boğazları are a series of internationally significant waterways in...