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Pancreatoblastoma

pancreatoblastoma in adults, pancreatoblastoma pathology outlines
Pancreatoblastoma is a rare type of pancreatic cancer1

It occurs mainly in childhood23 and has a relatively good prognosis

Contents

  • 1 Symptoms
  • 2 Pathology
  • 3 Treatment
  • 4 References

Symptomsedit

Children with pancreatoblastoma rarely present with early-stage disease, instead, most present with locally advanced or metastatic disease Common presenting symptoms include abdominal pain, emesis, and jaundice A multidisciplinary approach including good clinical history, state of the art imaging, and careful pathology is often needed to establish the correct diagnosis4

Pathologyedit

Resected pancreatoblastomas can be quite large, ranging from 2 centimeters to 20 centimeters in size 1 to 8 inches They are typically solid, soft masses Under the microscope, at least two cell types are seen: cells with “acinar” differentiation, and cells forming small “squamoid” nests The cells with acinar differentiation have some features of the normal acinar cell of the pancreas the most common cell in the normal pancreas5

Treatmentedit

If the tumor is operable, the first line of therapy should be surgical resection Then, after surgical resection, adjuvant chemotherapy should be given, even in stage I disease In patients with inoperable disease, chemotherapy alone should be given6 A multi-disciplinary approach to the treatment, including surgeons, oncologists, pathologists, radiologists, and radiation oncologists, is often the best approach to managing these patients4

Referencesedit

  1. ^ "Pancreatoblastoma" 
  2. ^ Saif MW 2007 "Pancreatoblastoma" JOP 8 1: 55–63 PMID 17228135 
  3. ^ Naik VR, Jaafar H, Leow VM, Bhavaraju VM March 2006 "Pancreatoblastoma: a rare tumour accidentally found" PDF Singapore Med J 47 3: 232–4 PMID 16518559 
  4. ^ a b "Pancreatic Cancer Multi-Disciplinary Clinic at Johns Hopkins University" 
  5. ^ "Pancreatic Cancer Frequently Asked Questions" 
  6. ^ http://wwworphanet/data/patho/GB/uk-pancreapdf -

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Pancreatoblastoma Information about

Pancreatoblastoma


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    Pancreatoblastoma beatiful post thanks!

    29.10.2014


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