Mycoplasma pneumonia


Mycoplasma pneumonia also known as "walking pneumonia" because its patients can sometimes continue to walk about while suffering from its symptoms is a form of bacterial pneumonia caused by the bacterial species Mycoplasma pneumoniae

Contents

  • 1 Pathophysiology
  • 2 Diagnosis
  • 3 Treatment
  • 4 See also
  • 5 References

Pathophysiologyedit

Mycoplasma pneumoniae is spread through respiratory droplet transmission Once attached to the mucosa of a host organism, M pneumoniae extracts nutrients, grows, and reproduces by binary fission Attachment sites include the upper and lower respiratory tract, causing pharyngitis, bronchitis, and pneumonia The infection caused by this bacterium is called atypical pneumonia because of its protracted course and lack of sputum production and wealth of extrapulmonary symptoms Chronic Mycoplasma infections have been implicated in the pathogenesis of rheumatoid arthritis and other rheumatological diseases

Mycoplasma atypical pneumonia can be complicated by Stevens–Johnson syndrome, autoimmune hemolytic anemia, cardiovascular diseases, encephalitis, or Guillain–Barré syndrome

Diagnosisedit

M pneumoniae infections can be differentiated from other types of pneumonia by the relatively slow progression of symptoms A positive blood test for cold-hemagglutinins in 50-70% of patients after 10 days of infection cold-hemagglutinin-test should be used with caution or not at all, since 50% of the tests are false-positive, lack of bacteria in a Gram-stained sputum sample, and a lack of growth on blood agar

PCR has also been used1

Treatmentedit

While antibiotics with activity specifically against M pneumoniae are often used eg, erythromycin, doxycycline, it is unclear if these result in greater benefit than using antibiotics without specific activity against this organism in those with an infection acquired in the community2

See alsoedit

  • Mycoplasmal pneumonia of swine

Referencesedit

  1. ^ Waris ME, Toikka P, Saarinen T, et al November 1998 "Diagnosis of Mycoplasma pneumoniae pneumonia in children" J Clin Microbiol 36 11: 3155–9 PMC 105292  PMID 9774556 
  2. ^ Biondi, E; McCulloh, R; Alverson, B; Klein, A; Dixon, A Jun 2014 "Treatment of mycoplasma pneumonia: a systematic review" Pediatrics 133 6: 1081–90 PMID 24864174 doi:101542/peds2013-3729 


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