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Mesomark assay

mesomark assay meaning, mesomark assayer
The Mesomark Assay is an in vitro test to monitor and possibly diagnose Pleural Mesothelioma and Peritoneal Mesothelioma1

Developed by Fujirebio Diagnostics and approved in late January 2007 by the US Food and Drug Administration FDA, it works by measuring levels of soluble mesothelin-related proteins SMRPs released by diseased mesothelioma cells The SMRP levels correlate directly with tumor volume thus permitting less invasive monitoring and improved assessment of treatment response

The MESOMARK assay is the most well-known and the world's first blood serum-based test for diagnosing mesothelioma However, as certain types of tumors such as sarcomatoid mesothelioma do not release SMRP, the FDA recommends that doctors use the MESOMARK assay in conjunction with other tests to ensure an accurate mesothelioma diagnosis2

In the future, the test may be used as an early detection measure as evidenced by recently sponsored tests by the Early Detection Research Network of the National Cancer Institute 1

Referencesedit

  1. ^ Beyer HL, Geschwindt RD, et al April 2007 "MESOMARK: a potential test for malignant pleural mesothelioma" Clinical Chemistry 53 4: 666–672 PMID 17289801 doi:101373/clinchem2006079327 
  2. ^ "MESOMARK in the News" 2014-08-22 

External linksedit

  • Fujirebio Diagnostics Homepage


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Mesomark assay


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    Mesomark assay beatiful post thanks!

    29.10.2014


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