Linuronlinuron herbicide, linuron
Linuron 3-3,4-dichlorophenyl-1-methoxy-1-methylurea is a phenylurea herbicide that is used to control the growth of grass and weeds for the purpose of supporting the growth of crops like soybeans
- 1 Pharmacology
- 11 Mechanism of action
- 2 Effects in animals
- 3 See also
- 4 References
Mechanism of action
Linuron acts via inhibition of photosystem II, which is necessary for photosynthetic electron transport in plants
Effects in animals
Linuron has been found to produce reproductive toxicity in animals by acting as an androgen receptor AR antagonist, and for this reason, is considered to be an endocrine disruptor Consequently, in January 2017, the European Commission Standing Committee on Plants, Animals, Food and Feed SCoPAFF decided to not renew its regulatory approval Sales are expected to cease by June 2017
- ^ Maier-Bode, H; Härtel, K 1981 "Linuron and monolinuron" 77: 1–243 doi:101007/978-1-4612-5874-2_1 ISSN 0179-5953
- ^ a b c Steven Mercurio 30 August 2016 Understanding Toxicology Jones & Bartlett Learning pp 705– ISBN 978-1-284-12761-4
- ^ a b T R Roberts; Terry R Roberts 1998 Metabolic Pathways of Agrochemicals Royal Society of Chemistry pp 744– ISBN 978-0-85404-494-8
- ^ "Peer review of the pesticide risk assessment of the active substance linuron" EFSA Journal 14 7 July 2016 doi:102903/jefsa20164518
- ^ a b Curtis, Marianne "Linuron fails to gain renewed approval" fginsightcom Briefing Media Ltd Retrieved 24 May 2017
|See also Receptor/signaling modulators Androgens and antiandrogens Estrogen receptor modulators Progesterone receptor modulators List of androgens/anabolic steroids|
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