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Foundation for Biomedical Research

foundation for biomedical research, foundation for biomedical research animal testing
Main articles
Animal testing
Alternatives to animal testing
Testing on: invertebrates
frogs · primates
rabbits · rodents
Animal testing regulations
History of animal testing
History of model organisms
IACUC
Laboratory animal sources
Pain and suffering in lab animals
Testing cosmetics on animals
Toxicology testing
Vivisection

Issues
Biomedical research
Animal rights · Animal welfare
Animals Scientific Procedures
Great ape research ban
International trade in primates

Cases
Brown Dog affair
Cambridge University primates
Pit of despair
Silver Spring monkeys
UCR 1985 laboratory raid
Unnecessary Fuss

Companies
Jackson Laboratory
Charles River Laboratories, Inc
Covance · Harlan
Huntingdon Life Sciences
UK lab animal suppliers
Nafovanny · Shamrock

Groups/campaigns
AALAS · AAAS · ALF
Americans for Medical Progress
Boyd Group · BUAV
Dr Hadwen Trust
Foundation for Biomedical
Research · FRAME
National Anti-Vivisection Society
New England Anti-Vivisection Society
PETA · Physicians Committee
for Responsible Medicine
Primate Freedom Project
Pro-Test
SPEAK · SHAC
Speaking of Research
Understanding Animal Research

Writers/activists
Tipu Aziz · Michael Balls
Neal Barnard · Colin Blakemore
Simon Festing · Gill Langley
Ingrid Newkirk · Bernard Rollin
Jerry Vlasak · Syed Ziaur Rahman

Categories
Animal testing · Animal rights
Animal welfare

Related templates
Template:Animal rights

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The Foundation for Biomedical Research FBR is an American non profit organization, 501c3, located in Washington, DC Established in 1981, the organization is dedicated to informing the news media, teachers, and other groups about the need for lab animals in medical and scientific research The organization, together with its partner, the National Association for Biomedical Research NABR, argues that promoting animal research leads to improved health for both humans and animals1

Its founding president is Frankie Trull

Contents

  • 1 Animal research
    • 11 Nonhuman Primates
    • 12 Dogs
    • 13 Cats
    • 14 Mice and Rats
  • 2 Activities
  • 3 See also
  • 4 References
  • 5 External links

Animal researchedit

According to the US Department of Agriculture USDA, the total number of animals used in that country in 2005 was almost 12 million,2 excluding rats and mice34 Some animal rights supporters believe that alternatives exist for animal models in research; however the vast majority of scientists believe there are no adequate alternatives which truly replace the roles which research animals play567 In fact, recent research shows that 98% of the current drug pipeline relies on either dogs or non-human primates

This graphic depicts several advances made with nonhuman primate research and a series of pie charts which show the percentages of total lab animals by species

According to the Foundation for Biomedical Research, animal research has been responsible for every medical breakthrough over the past century, although this position has been disputed by some animal rights activists and organizations891011 It cites animal research as leading to advances in antibiotics, blood transfusions, dialysis, organ transplantation, vaccinations, chemotherapy, bypass surgery, joint replacement, and methods for prevention, treatment, cure and control of disease, pain and suffering

Nonhuman Primatesedit

Nonhuman primates have been at the forefront of animal research controversy over the last several years even though they represent less than one percent of all animals models used1213 In August 2016, to counter criticism from animal rights' groups, a white paper coauthored by nine of the most premier scientific groups and titled The Critical Role of Nonhuman Primates in Medical Research was released14 Because of their incredible similarity to humans, primates such as rhesus macaques and chimpanzees, up until the National Institutes of Health ended public funding for chimpanzee research,15 have greatly contributed to many areas of medicine Some specific advances, according to the white paper, are: the development of the MMR vaccine, the treatment of leprosy, HIV medication, a vaccine for hepatitis B, and improvements in cancer treatment1617 One of the most recent advancements has been the development of a highly effective vaccine against the Zika virus, which should soon be protecting both the people and primates that are most at risk of infection18

Dogsedit

Dogs have been used in research for decades and have been invaluable for treating many human and canine illnesses Dogs contract many of the diseases humans do, from heart disease to cancer and they are also exposed to the same environment as humans Canine research has led to many significant breakthroughs such as hip replacements, development of cancer treatments, and research in stem cells, diabetes, and Alzheimer's disease19 Treatments for heartworms, parasites, and vaccinations against parvovirus, rabies, and canine distemper have also come from canine models13

Catsedit

Cats, like dogs, have also proven to be extremely helpful for developing treatments for both human and feline diseases Cats have been a mainstay in research studies of neurological, cardiovascular, and respiratory diseases and the immune system In particular, they have been valuable models for understanding the function of the neuron, the chemical transmission of nerve impulses, and the functional organization of the brain Neuroscientists studying cats have provided a map of the circuitry of the vertebral cortex revealing the major pathways that send signals from the eye to the brain20 Cats have also been invaluable for the treatment of leukemia and both feline and human breast cancer20 Feline leukemia used to be one of the most common killers of cats and about 85% died within three years of their diagnosis However, with their help, scientists have developed a vaccine for feline leukemia and now more beloved pets get to spend more time with their families

Mice and Ratsedit

In the US, the numbers of rats and mice used in animal research is estimated at 20 million a year, or 95% of the total number of lab animals412 Other rodents commonly used are guinea pigs, hamsters, and gerbils Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate21 Mice also have genomes that are very similar to the human genome This similarity allows researchers to recreate human diseases, such as breast cancer, in mice in order to understand how genes affect the development of disease13 The Foundation advocates the highest quality of animal care and treatment, stating that the use of animals in research is a privilege, and that animals deserve our respect and the best possible care

Activitiesedit

The Foundation for Biomedical Research conducts educational programs for the news media, teachers, students and parents, pet owners and other groups

FBR publishes a subscriber-based daily news service called Total E-clips featuring biomedical research news, medical breakthroughs, political and legislative and activism news

Since 1981, the FBR has monitored and analyzed the activities of animal rights organizations relating to researchers and institutions

See alsoedit

  • Animal testing
  • History of animal testing

Referencesedit

  1. ^ Foundation for Biomedical Research "About FBR" Retrieved 2009-06-24 
  2. ^ 2005 Report on Enforcement of the Animal Welfare Act US Department of Agriculture, Accessed 8 February 2008
  3. ^ The humane care and treatment of laboratory animals Archived March 8, 2008, at the Wayback Machine National Association of Biomedical Research, Accessed 8 February 2008
  4. ^ a b Trull, Frankie L; Rich, Barbara A 1999 "More Regulation of Rodents" Science 284 5419: 1463 doi:101126/science28454191463 
  5. ^ Sir John Vane "Animal research and medical progress" 
  6. ^ About animal testing "Scientists Against Animal Testing" 
  7. ^ The Society for Neuroscience "Policies on the Use of Animals and Humans in Neuroscience Research" 
  8. ^ Ruesch, Hans 1989 1000 Doctors and many more Against Vivisection Civis/Civitas ASIN B000FJGF82 
  9. ^ Animal Experimentation Issues PCRM Archived July 23, 2011, at the Wayback Machine
  10. ^ "The Johns Hopkins Center for Alternatives to Animal Testing CAAT" Retrieved 2009-06-24 
  11. ^ PETA "Animals in Experimentation – Everybody Loses" PDF Retrieved 2009-06-24 
  12. ^ a b The Critical Role of Nonhuman Primates in Research, https://fbresearchorg/wp-content/uploads/2016/08/NHP-White-Paper-Print-08-22-16pdf pg 11
  13. ^ a b c "MONKEYRESEARCHORG" monkeyresearchorg Retrieved 2017-02-21 
  14. ^ "Nine Premier Scientific Groups Release White Paper on the Critical Role of Nonhuman Primates NHPs in Scientific and Medical Research - Foundation for Biomedical Research" Foundation for Biomedical Research 2016-08-24 Retrieved 2017-02-21 
  15. ^ "NIH Will No Longer Support Biomedical Research on Chimpanzees" National Institutes of Health NIH 2015-11-18 Retrieved 2017-02-21 
  16. ^ The Critical Role of Nonhuman Primates in Medical Research, https://fbresearchorg/wp-content/uploads/2016/08/NHP-White-Paper-Print-08-22-16pdf pg 9-10
  17. ^ https://fbresearchorg/wp-content/uploads/2016/09/Benefits-of-Monkey-Research-online-brochurepdf
  18. ^ "Powerful Zika vaccine protects mice and monkeys from the virus" New Scientist Retrieved 2017-02-21 
  19. ^ Dogs: The Essential Need for Animals in Medical Research, https://fbresearchorg/wp-content/uploads/2016/04/Dogs-In-Biomedical-Research-FBRpdf
  20. ^ a b "Cats | NABR" wwwnabrorg Retrieved 2017-02-21 
  21. ^ Rosenthal, N; Brown, S 2007 "The mouse ascending: perspectives for human-disease models" Nature Cell Biology 9 9: 993–9 PMID 17762889 doi:101038/ncb437 

External linksedit

  • FBR website
  • NABR website
  • The Lifesaving Benefits of Primate Research
  • NHP White Paper

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Foundation for Biomedical Research


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    29.10.2014


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