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Florfenicol

florfenicol antibiotic, florfenicol
Florfenicol marketed by Schering-Plough Animal Health under the trade name Nuflor is a fluorinated synthetic analog of thiamphenicol , mainly used in veterinary medicine

As a generic, it is now available worldwide 

Contents

  • 1 Indications
  • 2 Contamination
  • 3 External links
  • 4 References

Indications

In the United States, florfenicol is currently indicated for the treatment of bovine respiratory disease BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, for treatment of bovine interdigital phlegmon foot rot, acute interdigital necrobacillosis, infectious pododermatitis associated with Fusobacterium necrophorum and Bacteroides melaninogenicus

Florfenicol is also used in aquaculture, and is licensed for use in the United States for the control of enteric septicemia in catfish

Since the early 2000s, it is used in Europe , treating mainly primary or secondary colibacillosis in broiler  and parent flocks It is not allowed in laying hens, due to residues in eggs It is also indicated in turkey

The use of florfenicol in horses, and likely in other equids, typically causes diarrhea This has been anecdotally reported to progress to lethal cases of acute colitis Therefore, use of this antimicrobial in the equine patient should be limited to cases in which other, safer, options are not available

Contamination

Florfenicol was among the drug contaminants in a brand of supermarket eggs in Taiwan and Iran

External links

  • Nuflor website

References

  1. ^ Syriopoulou VP, Harding AL, Goldmann DA, Smith AL February 1981 "In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol" Antimicrob Agents Chemother 19 2: 294–7 doi:101128/aac192294 PMC 181412  PMID 6957162 
  2. ^ https://wwwdrugscom/international/florfenicolhtml
  3. ^ Gaunt, P S; Langston, C; Wrzesinski, C; Gao, D; Adams, P; Crouch, L; Sweeney, D; Endris, R "Multidose pharmacokinetics of orally administered florfenicol in the channel catfish " Journal of Veterinary Pharmacology and Therapeutics 36 5: 502–506 doi:101111/j1365-2885201201426x 
  4. ^ http://wwwemaeuropaeu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500014277pdf
  5. ^ Shen, J; Wu, X; Jiang, H "Pharmacokinetics of florfenicol in healthy and Escherichia coli-infected broiler chickens" Research in Veterinary Science 73 2: 137–140 doi:101016/s0034-52880200033-4 
  6. ^ Robinson, NE; Sprayberry, KA 2009 Current therapy in equine medicine Saunders Elesevier p 13 ISBN 978-1-4160-5475-7 Retrieved March 21, 2011 
  7. ^ Lee I-chia 8 January 2013 "Survey suggests certain eggs may be dangerous" Taipei Times Retrieved 3 November 2014 

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Florfenicol Information about

Florfenicol


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    Florfenicol beatiful post thanks!

    29.10.2014


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