Mon .19 Oct 2019
TR | RU | UK | KK | BE |

CRYM, cryme tyme

IdentifiersAliasesCRYM, DFNA40, THBP, crystallin muExternal IDsMGI:102675 HomoloGene:1424 GeneCards:CRYM
Gene location Human
ChrChromosome 16 human
Band16p122Start21,238,874 bp
End21,303,083 bp
RNA expression pattern
More reference expression data
RefSeq mRNA



RefSeq protein



Location UCSCChr 16:2124 – 213 MbChr 7:12019 – 1202 MbPubMed searchWikidata
^ "Mouse PubMed Reference:" 
  • ^ Chen H, Phillips HA, Callen DF, Kim RY, Wistow GJ, Antonarakis SE Feb 1993 "Localization of the human gene for mu-crystallin to chromosome 16p" Genomics 14 4:1115–6 doi:101016/S0888-75430580143-0 PMID 1478656 
  • ^ a b "Entrez Gene:CRYM crystallin, mu" 
  • ^ Hallen A, Cooper AJ, Jamie JF, Haynes PA, Willows RD February 2011 "Mammalian forebrain ketimine reductase identified as μ-crystallin; potential regulation by thyroid hormones" J Neurochem 118 3:no–no doi:101111/j1471-4159201107220x PMID 21332720 
  • ^ Oshima A, Suzuki S, Takumi Y, Hashizume K, Abe S, Usami S June 2006 "CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea" J Med Genet 43 6:e25 doi:101136/jmg2005034397 PMC 2564543  PMID 16740909 
  • ^ Abe S, Katagiri T, Saito-Hisaminato A, Usami S, Inoue Y, Tsunoda T, Nakamura Y January 2003 "Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues" Am J Hum Genet 72 1:73–82 doi:101086/345398 PMC 420014  PMID 12471561 
  • ^ Suzuki S, Suzuki N, Mori J, Oshima A, Usami S, Hashizume K April 2007 "micro-Crystallin as an intracellular 3,5,3'-triiodothyronine holder in vivo" Mol Endocrinol 21 4:885–94 doi:101210/me2006-0403 PMID 17264173 
  • ^ Dietrich JW 2002 Der Hypophysen-Schilddrüsen-Regelkreis Entwicklung und klinische Anwendung eines nichtlinearen Modellsin German Berlin:Logos-Verlag ISBN 3-89722-850-5 
  • ^ Dietrich JW, Tesche A, Pickardt CR, Mitzdorf U 2004 "Thyrotropic Feedback Control:Evidence for an Additional Ultrashort Feedback Loop from Fractal Analysis" Cybernetics and Systems 35 4:315–31 doi:101080/01969720490443354 
  • External links

    • Human CRYM genome location and CRYM gene details page in the UCSC Genome Browser

    Further reading

    • Kim RY, Gasser R, Wistow GJ 1992 "mu-crystallin is a mammalian homologue of Agrobacterium ornithine cyclodeaminase and is expressed in human retina" Proc Natl Acad Sci USA 89 19:9292–6 doi:101073/pnas89199292 PMC 50112  PMID 1384048 
    • Vié MP, Blanchet P, Samson M, et al 1996 "High affinity thyroid hormone-binding protein in human kidney:kinetic characterization and identification by photoaffinity labeling" Endocrinology 137 11:4563–70 doi:101210/en137114563 PMID 8895318 
    • Segovia L, Horwitz J, Gasser R, Wistow G 1998 "Two roles for mu-crystallin:a lens structural protein in diurnal marsupials and a possible enzyme in mammalian retinas" Mol Vis 3:9 PMID 9285773 
    • Vié MP, Evrard C, Osty J, et al 1998 "Purification, molecular cloning, and functional expression of the human nicodinamide-adenine dinucleotide phosphate-regulated thyroid hormone-binding protein" Mol Endocrinol 11 11:1728–36 doi:101210/me11111728 PMID 9328354 
    • Loftus BJ, Kim UJ, Sneddon VP, et al 1999 "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q" Genomics 60 3:295–308 doi:101006/geno19995927 PMID 10493829 
    • Abe S, Katagiri T, Saito-Hisaminato A, et al 2003 "Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues" Am J Hum Genet 72 1:73–82 doi:101086/345398 PMC 420014  PMID 12471561 
    • Strausberg RL, Feingold EA, Grouse LH, et al 2003 "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" Proc Natl Acad Sci USA 99 26:16899–903 doi:101073/pnas242603899 PMC 139241  PMID 12477932 
    • Gerhard DS, Wagner L, Feingold EA, et al 2004 "The status, quality, and expansion of the NIH full-length cDNA project:the Mammalian Gene Collection MGC" Genome Res 14 10B:2121–7 doi:101101/gr2596504 PMC 528928  PMID 15489334 
    • Reed PW, Corse AM, Porter NC, et al 2007 "Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy" Exp Neurol 205 2:583–6 doi:101016/jexpneurol200703009 PMID 17451686 

    crimea, crymca,, cryme tyme, crymes pittman, crymice, crymod, crymonix, crymore, cymax

    CRYM Information about


    • user icon

      CRYM beatiful post thanks!


    CRYM viewing the topic.
    CRYM what, CRYM who, CRYM explanation

    There are excerpts from wikipedia on this article and video

    Random Posts

    La Porte, Indiana

    La Porte, Indiana

    La Porte French for "The Door" is a city in LaPorte County, Indiana, United States, of which it is t...
    Fernando Montes de Oca Fencing Hall

    Fernando Montes de Oca Fencing Hall

    The Fernando Montes de Oca Fencing Hall is an indoor sports venue located in the Magdalena Mixhuca S...
    My Everything (The Grace song)

    My Everything (The Grace song)

    "My Everything" was Grace's 3rd single under the SM Entertainment, released on November 6, 2006 Unli...
    Turkish Straits

    Turkish Straits

    The Turkish Straits Turkish:Türk Boğazları are a series of internationally significant waterways in...