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Cochlear nerve

cochlear nerve function, cochlear nerve inflammation
The cochlear nerve also auditory or acoustic nerve is one of two parts of the vestibulocochlear nerve, a cranial nerve present in amniotes, the other part being the vestibular nerve The cochlear nerve carries auditory sensory information from the cochlea of the inner ear directly to the brain The other portion of the vestibulocochlear nerve is the vestibular nerve, which carries spatial orientation information to the brain from the semicircular canals, also known as semicircular ducts


  • 1 Anatomy and connections
  • 2 Types of neurons
  • 3 Cochlear nuclear complex
  • 4 See also
  • 5 References
  • 6 Additional images
  • 7 External links

Anatomy and connectionsedit

In terms of anatomy, an auditory nerve fiber is either bipolar or unipolar, with its distal projection being called the peripheral process, and its central projection being called the axon; these two projections are also known as the "peripheral axon" and the "central axon", respectively The peripheral process is sometimes referred to as a dendrite, although that term is somewhat inaccurate Unlike the typical dendrite, the peripheral process generates and conducts action potentials, which then "jump" across the cell body or soma and continue to propagate along the central axon In this respect, auditory nerve fibers are somewhat unusual in that action potentials pass through the soma Both the peripheral process and the axon are myelinated

In humans, there are on average 30,000 nerve fibers within the cochlear nerve1 The number of fibers varies significantly across species; the domestic cat, for example, has an average of 50,000 fibers The peripheral axons of auditory nerve fibers form synaptic connections with the hair cells of the cochlea via ribbon synapses using the neurotransmitter glutamate The central axons form synaptic connections with cells in the cochlear nucleus of the brainstem

The cell bodies of the cochlear nerve lie within the cochlea and collectively form the spiral ganglion, named for the spiral shape it shares with the cochlea These central axons exit the cochlea at its base and form a nerve trunk, which, in humans, is approximately one inch long This travels in parallel with the vestibular nerves through the internal auditory canal, through which it connects to the brainstem There, its fibers synapse with the cell bodies of the cochlear nucleus

Types of neuronsedit

In mammals, cochlear nerve fibers are classified as either type I or type II

  • Type I neurons make up 90-95% of the neurons and innervate the inner hair cells They have relatively large diameters, are bipolar, and are myelinated Each type I axon innervates only a single inner hair cell, but each inner hair cell is innervated by up to 30 such nerve fibers, depending on species and location within the cochlea
  • Type II neurons make up the remaining 5-10% of the neurons and innervate the outer hair cells They have relatively small diameters, are unipolar, and are unmyelinated

Cochlear nuclear complexedit

In mammals, the axons from each cochlear nerve terminate in the cochlear nuclear complex that is ipsilaterally located in the medulla of the brainstem The cochlear nucleus is the first 'relay station' of the central auditory system and receives mainly ipsilateral afferent input

The three major components of the cochlear nuclear complex are see figure below:

  • the dorsal cochlear nucleus DCN
  • the anteroventral cochlear nucleus AVCN
  • the posteroventral cochlear nucleus PVCN

Each of the three cochlear nuclei are tonotopically organized The axons from the low-frequency region of the cochlea project to the ventral portion of the dorsal cochlear nucleus and the ventrolateral portions of the anteroventral cochlear nucleus The axons from the high-frequency region project to the dorsal portion of the anteroventral cochlear nucleus and the uppermost dorsal portions of the dorsal cochlear nucleus The axons from the intermediate frequency region project to intermediate targets, such that tonotopy is preserved between the cochlea and the cochlear nuclei

See alsoedit

  • Cochlear implant


  1. ^ Spoendlin H, Schrott A 1989 "Analysis of the human auditory nerve" Hear Res 43 1: 25–38 PMID 2613564 doi:101016/0378-59558990056-7 

Additional imagesedit

External linksedit

  • Illustration at cytochemistrynet
  • Gray's page #1059

cochlear nerve anatomy, cochlear nerve aplasia, cochlear nerve damage, cochlear nerve deficiency, cochlear nerve fibers, cochlear nerve function, cochlear nerve hypoplasia, cochlear nerve inflammation, cochlear nerve pathway, cochlear nerve remote frequency stimulation

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Cochlear nerve

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