Tue . 19 Apr 2019

Cefamandole

cefamandole nafate, cefamandole injection brand and strength
Cefamandole INN, also known as cephamandole is a second-generation broad-spectrum cephalosporin antibiotic The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally Cefamandole is no longer available in the United States

The chemical structure of cefamandole, like that of several other cephalosporins, contains an N-methylthiotetrazole NMTT or 1-MTT side chain As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia likely due to inhibition of the enzyme vitamin K epoxide reductasevitamin K supplement is recommended during therapy and a reaction with ethanol similar to that produced by disulfiram Antabuse, due to inhibition of aldehyde dehydrogenase

Cefamandole has a broad spectrum of activity and can be used to treat bacterial infections of the skin, bones and joints, urinary tract, and lower respiratory tract The following represents cefamandole MIC susceptibility data for a few medically significant microorganisms

  • Escherichia coli: 012 - 400 μg/ml
  • Haemophilus influenzae: 006 - >16 μg/ml
  • Staphylococcus aureus: 01 - 125 μg/ml

CO2 is generated during the normal constitution of cefamandole and ceftazidime, potentially resulting in an explosive-like reaction in syringes

See also

  • Cefazolin
  • Ceforanide

References

  1. ^ http://wwwtoku-ecom/Assets/MIC/Cefamandole%20sodium%20saltpdf
  2. ^ Stork CM 2006 "Antibiotics, antifungals, and antivirals" In Nelson LH, Flomenbaum N, Goldfrank LR, Hoffman RL, Howland MD, Lewin NA Goldfrank's toxicologic emergencies New York: McGraw-Hill p 847 ISBN 0-07-143763-0 Retrieved 2009-07-03 

cefamandole, cefamandole, cefamandole generation, cefamandole generation, cefamandole injection, cefamandole injection, cefamandole injection brand and strength, cefamandole injection brand and strength, cefamandole nafate, cefamandole nafate, cefamandole nafate for injection, cefamandole nafate for injection, cefamandole package, cefamandole package, cefamandole pic, cefamandole pic, cefamandole structure, cefamandole structure


Cefamandole Information about

Cefamandole


  • user icon

    Cefamandole beatiful post thanks!

    29.10.2014


Cefamandole
Cefamandole
Cefamandole viewing the topic.
Cefamandole what, Cefamandole who, Cefamandole explanation

There are excerpts from wikipedia on this article and video

Random Posts

IP address blocking

IP address blocking

IP address blocking prevents connection between a server or website and certain IP addresses or rang...
Gisele Bündchen

Gisele Bündchen

Gisele Caroline Bündchen1 Portuguese pronunciation: ʒiˈzɛli kaɾoˈlini ˈbĩtʃẽj, German pronuncia...
Sheldon, West Midlands

Sheldon, West Midlands

Sheldon is an area of east Birmingham, England Historically part of Warwickshire, it is close to the...
Beverly, Chicago

Beverly, Chicago

Beverly is one of the 77 community areas of Chicago, Illinois It is located on the South Side on the...