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C-reactive protein

c-reactive protein normal range, c-reactive protein test
1B09, 1GNH, 1LJ7, 3L2Y, 3PVN, 3PVO

Identifiers Aliases CRP, PTX1, C-reactive protein, pentraxin-related, C-Reactive Protein External IDs OMIM: 123260 MGI: 88512 HomoloGene: 128039 GeneCards: CRP RNA expression pattern

More reference expression data Orthologs Species Human Mouse Entrez
Ensembl
UniProt
RefSeq mRNA

NM_000567
NM_001329057
NM_001329058

NM_007768

RefSeq protein

NP_000558
NP_001315986
NP_001315987

NP_031794

Location UCSC Chr 1: 15971 – 15971 Mb Chr 1: 1727 – 17283 Mb PubMed search 1 2 Wikidata
  • C-reactive protein

  • C-reactive protein

  • Referencesedit

    1. ^ "Human PubMed Reference:" 
    2. ^ "Mouse PubMed Reference:" 
    3. ^ Thompson D, Pepys MB, Wood SP Feb 1999 "The physiological structure of human C-reactive protein and its complex with phosphocholine" Structure 7 2: 169–77 PMID 10368284 doi:101016/S0969-21269980023-9 
    4. ^ a b c d e f g Pepys MB, Hirschfield GM Jun 2003 "C-reactive protein: a critical update" The Journal of Clinical Investigation 111 12: 1805–12 PMC 161431  PMID 12813013 doi:101172/JCI18921 
    5. ^ a b Lau DC, Dhillon B, Yan H, Szmitko PE, Verma S May 2005 "Adipokines: molecular links between obesity and atheroslcerosis" American Journal of Physiology Heart and Circulatory Physiology 288 5: H2031–41 PMID 15653761 doi:101152/ajpheart010582004 
    6. ^ Mantovani A, Garlanda C, Doni A, Bottazzi B Jan 2008 "Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3" Journal of Clinical Immunology 28 1: 1–13 PMID 17828584 doi:101007/s10875-007-9126-7 
    7. ^ Ananthanarayan R, Paniker C 1978 Ananthanarayan and Paniker's Textbook of Microbiology 7th ed Himayatnagar, Hyderabad: Orient Longman p 218 ISBN 9788125028086 
    8. ^ Tillett WS, Francis T Sep 1930 "Serological reactions in pneumonia with a nonprotein somatic fraction of pneumococcus" The Journal of Experimental Medicine 52 4: 561–71 PMC 2131884  PMID 19869788 doi:101084/jem524561 
    9. ^ Kennelly PJ, Murray RF, Rodwell VW, Botham KM 2009 Harper's illustrated biochemistry McGraw-Hill Medical ISBN 0-07-162591-7 
    10. ^ Pincus MR, McPherson RA, Henry JB 2007 Henry's clinical diagnosis and management by laboratory methods Saunders Elsevier ISBN 1-4160-0287-1 
    11. ^ Ratey JJ, Noskin GA, Braun R, Hanley EN Jr, McInnes IB, Ruddy S 2008 Kelley's Textbook of Rheumatology: 2-Volume Set, Expert Consult: Online and Print Textbook of Rheumatology Kelley's2 Vol Philadelphia: Saunders ISBN 1-4160-3285-1 
    12. ^ https://wwwncbinlmnihgov/gene/1401
    13. ^ NCBI Entrez Protein #CAA39671
    14. ^ Enocsson H, Sjöwall C, Skogh T, Eloranta ML, Rönnblom L, Wetterö J December 2009 "Interferon-alpha mediates suppression of C-reactive protein: explanation for muted C-reactive protein response in lupus flares" Arthritis and Rheumatism 60 12: 3755–60 PMID 19950271 doi:101002/art25042 
    15. ^ "Normal results" C-reactive protein MedlinePlus Retrieved 23 April 2015 
    16. ^ Thomas, Lothar, Labor und Diagnose TH-Books, Frankfurt, 2008, p 1010
    17. ^ Clyne B, Olshaker JS 1999 "The C-reactive protein" The Journal of Emergency Medicine 17 6: 1019–25 PMID 10595891 doi:101016/S0736-46799900135-3 
    18. ^ a b c Liu S, Ren J, Xia Q, Wu X, Han G, Ren H, Yan D, Wang G, Gu G, Li J Dec 2013 "Preliminary case-control study to evaluate diagnostic values of C-reactive protein and erythrocyte sedimentation rate in differentiating active Crohn's disease from intestinal lymphoma, intestinal tuberculosis and Behcet's syndrome" The American Journal of the Medical Sciences 346 6: 467–72 PMID 23689052 doi:101097/MAJ0b013e3182959a18 unreliable medical source
    19. ^ Lu H, Ouyang W, Huang C Apr 2006 "Inflammation, a key event in cancer development" Molecular Cancer Research 4 4: 221–33 PMID 16603636 doi:101158/1541-7786MCR-05-0261 
    20. ^ Allin KH, Nordestgaard BG 2011 "Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer" Critical Reviews in Clinical Laboratory Sciences 48 4: 155–70 PMID 22035340 doi:103109/104083632011599831 
    21. ^ Erlinger TP, Platz EA, Rifai N, Helzlsouer KJ Feb 2004 "C-reactive protein and the risk of incident colorectal cancer" PDF JAMA 291 5: 585–90 PMID 14762037 doi:101001/jama2915585 
    22. ^ Baron JA, Cole BF, Sandler RS, Haile RW, Ahnen D, Bresalier R, McKeown-Eyssen G, Summers RW, Rothstein R, Burke CA, Snover DC, Church TR, Allen JI, Beach M, Beck GJ, Bond JH, Byers T, Greenberg ER, Mandel JS, Marcon N, Mott LA, Pearson L, Saibil F, van Stolk RU Mar 2003 "A randomized trial of aspirin to prevent colorectal adenomas" The New England Journal of Medicine 348 10: 891–9 PMID 12621133 doi:101056/NEJMoa021735 
    23. ^ Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM Jul 2001 "C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus" JAMA 286 3: 327–34 PMID 11466099 doi:101001/jama2863327 
    24. ^ Dehghan A, Kardys I, de Maat MP, Uitterlinden AG, Sijbrands EJ, Bootsma AH, Stijnen T, Hofman A, Schram MT, Witteman JC Mar 2007 "Genetic variation, C-reactive protein levels, and incidence of diabetes" Diabetes 56 3: 872–8 PMID 17327459 doi:102337/db06-0922 
    25. ^ Lopez-Garcia E, Schulze MB, Meigs JB, Manson JE, Rifai N, Stampfer MJ, Willett WC, Hu FB Mar 2005 "Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunction" The Journal of Nutrition 135 3: 562–6 PMID 15735094 
    26. ^ Danesh J, Wheeler JG, Hirschfield GM, Eda S, Eiriksdottir G, Rumley A, Lowe GD, Pepys MB, Gudnason V Apr 2004 "C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease" The New England Journal of Medicine 350 14: 1387–97 PMID 15070788 doi:101056/NEJMoa032804 
    27. ^ Koenig, Wolfgang 2006 "C-reactive protein - a critical cardiovascular risk marker" CRPhealthcom
    28. ^ Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, Gray GA, Sabin CA, Jenvey MC, Kolstoe SE, Thompson D, Wood SP Apr 2006 "Targeting C-reactive protein for the treatment of cardiovascular disease" Nature 440 7088: 1217–21 PMID 16642000 doi:101038/nature04672 
    29. ^ Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ Nov 2008 "Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein" The New England Journal of Medicine 359 21: 2195–207 PMID 18997196 doi:101056/NEJMoa0807646 
    30. ^ Sindhu S, Singh HK, Salman MT, Fatima J, Verma VK Oct 2011 "Effects of atorvastatin and rosuvastatin on high-sensitivity C-reactive protein and lipid profile in obese type 2 diabetes mellitus patients" Journal of Pharmacology & Pharmacotherapeutics 2 4: 261–5 PMC 3198521  PMID 22025854 doi:104103/0976-500X85954 
    31. ^ Jialal I, Stein D, Balis D, Grundy SM, Adams-Huet B, Devaraj S Apr 2001 "Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels" Circulation 103 15: 1933–5 PMID 11306519 doi:101161/01CIR103151933 
    32. ^ Heart Protection Study Collaborative Group, Emberson J, Bennett D, Link E, Parish S, Danesh J, Armitage J, Collins R Feb 2011 "C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study" Lancet 377 9764: 469–76 PMC 3042687  PMID 21277016 doi:101016/S0140-67361062174-5 
    33. ^ Swardfager W, Herrmann N, Cornish S, Mazereeuw G, Marzolini S, Sham L, Lanctôt KL Apr 2012 "Exercise intervention and inflammatory markers in coronary artery disease: a meta-analysis" American Heart Journal 163 4: 666–76e1–3 PMID 22520533 doi:101016/jahj201112017 
    34. ^ Zacho J, Tybjaerg-Hansen A, Jensen JS, Grande P, Sillesen H, Nordestgaard BG Oct 2008 "Genetically elevated C-reactive protein and ischemic vascular disease" The New England Journal of Medicine 359 18: 1897–908 PMID 18971492 doi:101056/NEJMoa0707402 
    35. ^ St-Onge MP, Zhang S, Darnell B, Allison DB Apr 2009 "Baseline serum C-reactive protein is associated with lipid responses to low-fat and high-polyunsaturated fat diets" The Journal of Nutrition 139 4: 680–3 PMC 2666362  PMID 19297430 doi:103945/jn108098251 
    36. ^ Clearfield MB Sep 2005 "C-reactive protein: a new risk assessment tool for cardiovascular disease" The Journal of the American Osteopathic Association 105 9: 409–16 PMID 16239491 
    37. ^ Sidore, C; et al 2015 "Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers" Nature Genetics 47: 1272–1281 PMC 4627508  PMID 26366554 doi:101038/ng3368 
    38. ^ a b Latina JM, Estes NA, Garlitski AC 2013 "The Relationship between Obstructive Sleep Apnea and Atrial Fibrillation: A Complex Interplay" Pulmonary Medicine 2013: 621736 PMC 3600315  PMID 23533751 doi:101155/2013/621736 
    39. ^ Lloyd-Jones DM, Liu K, Tian L, Greenland P Jul 2006 "Narrative review: Assessment of C-reactive protein in risk prediction for cardiovascular disease" Annals of Internal Medicine 145 1: 35–42 PMID 16818927 doi:107326/0003-4819-145-1-200607040-00129 
    40. ^ Bower, JK; Lazo, M; Juraschek, SP; Selvin, E 2012 "Within-person variability in high-sensitivity C-reactive protein" Archives of Internal Medicine 172 19: 1519–1521 ISSN 1538-3679 PMC 3613132  PMID 22945505 doi:101001/archinternmed20123712 
    41. ^ Goldman, Lee 2011 Goldman's Cecil Medicine 24th ed Philadelphia: Elsevier Saunders p 54 ISBN 1437727883 
    42. ^ "hs-CRP" Retrieved June 3, 2013 
    43. ^ Ammitzbøll CG, Steffensen R, Bøgsted M, Hørslev-Petersen K, Hetland ML, Junker P, Johansen JS, Pødenphant J, Østergaard M, Ellingsen T, Stengaard-Pedersen K 2014 "CRP genotype and haplotype associations with serum C-reactive protein level and DAS28 in untreated early rheumatoid arthritis patients" Arthritis Research & Therapy 16 5: 475 PMC 4247621  PMID 25359432 doi:101186/s13075-014-0475-3 

    External linksedit

    • MedlinePlus Encyclopedia C-reactive protein
    • Inflammation, Heart Disease and Stroke: The Role of C-Reactive Protein American Heart Association
    • C-Reactive Protein at the US National Library of Medicine Medical Subject Headings MeSH
    • CRP at Lab Tests Online
    • CRP: analyte monograph - The Association for Clinical Biochemistry and Laboratory Medicine
    • George Vrousgos, ND - Southern Cross University
    • Human CRP genome location and CRP gene details page in the UCSC Genome Browser

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    C-reactive protein


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      C-reactive protein beatiful post thanks!

      29.10.2014


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