Brucella melitensis

Brucella neotomae

Brucella melitensis is a Gram-negative coccobacillus bacterium from the Brucellaceae family The bacterium causes ovine brucellosis, along with Brucella ovis It can infect sheep, cattle, and sometimes humans, and it can be transmitted by the stable fly It is zoonotic, unlike B ovis, causing Malta fever or localized brucellosis in humans

Brucella melitensis colonies growing on agar


  • 1 Pathogenesis and disease
  • 2 History
  • 3 References
  • 4 External links

Pathogenesis and diseaseedit

The bacterium causes severe inflammation of the epididymis, with formation of spermatocoeles and fibrinous adhesions This disease is known as ovine brucellosis, and is a reportable disease in the USA1 It can also cause epididymitis in cattle, and reproductive disease such as orchitis, mastitis, and abortionscitation needed


In 1887, M melitensis was isolated in Malta by David Bruce from the spleen of a soldier who had died from acute brucellosis2 The mechanism of transmission was not determined until 1905, when Temi Żammit found that apparently healthy goats could infect humans with M melitensis via their milk3


  1. ^ "Reportable and Foreign Animal Diseases" PDF USDAgov USDA Retrieved 2017-02-04 
  2. ^ Galińska, EM; Zagórski, J 2013 "Brucellosis in humans--etiology, diagnostics, clinical forms" Annals of agricultural and environmental medicine : AAEM 20 2: 233–8 PMID 23772567 
  3. ^ Wyatt, HV 2005 "How Themistocles Zammit found Malta Fever brucellosis to be transmitted by the milk of goats" Journal of the Royal Society of Medicine 98 10: 451–454 PMC 1240100  PMID 16199812 doi:101258/jrsm9810451 
  • Brucella melitensis, reviewed and published by Wikivet at http://enwikivetnet/Brucella_melitensis, accessed 2011-08-24

External linksedit

  • Brucella melitensis genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID
  • Brucella melitensis 16M genome information
  • Brucella melitensis in African wildlife diseases

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Brucella melitensis
Brucella melitensis

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