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basopenia symptoms, basopenia
Basopenia or basocytopenia is a form of agranulocytosis associated with a deficiency of basophils[1]

It has been proposed as an indicator of ovulation[2]It is difficult to detect without flow cytometry, because normal levels are so low[3]

It can be defined as less than 001 x 109 / L[4]

Associated conditions

  • Hereditary absence of basophils very rare
  • Elevated levels of glucocorticoids
  • Hyperthyroidism or treatment with thyroid hormones
  • Ovulation
  • Hypersensitivity reactions
  • urticaria [5][6][7]
  • Anaphylaxis
  • Drug-induced reactions
  • Leukocytosis in association with diverse disorders


  1. ^ "Definition: basophilic leukopenia from Online Medical Dictionary" 
  2. ^ Soni R, Bose S, Gada D, Potnis V October 1996 "Basopenia as an indicator of ovulation a short term clinical study" Indian J Physiol Pharmacol 40 4: 385–8 PMID 9055113 
  3. ^ "CLS_3223_Unit 03_WBC" Archived from the original on 2009-01-30 
  4. ^ "Pathology" 
  5. ^ Lourenço FD, Azor MH, Santos JC May 2008 "Activated status of basophils in chronic urticaria leads to interleukin-3 hyper-responsiveness and enhancement of histamine release induced by anti-IgE stimulus" Br J Dermatol 158 5: 979–86 doi:101111/j1365-2133200808499x PMID 18341658 
  6. ^ Grattan CE, Dawn G, Gibbs S, Francis DM March 2003 "Blood basophil numbers in chronic ordinary urticaria and healthy controls: diurnal variation, influence of loratadine and prednisolone and relationship to disease activity" Clin Exp Allergy 33 3: 337–41 doi:101046/j1365-2222200301589x PMID 12614448 
  7. ^ Grattan CE, Walpole D, Francis DM December 1997 "Flow cytometric analysis of basophil numbers in chronic urticaria: basopenia is related to serum histamine releasing activity" Clin Exp Allergy 27 12: 1417–24 doi:101111/j1365-22221997tb02986x PMID 9433937 

External links

Classification D
  • ICD-10: D728
  • ICD-9-CM: 28859

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