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atoh1 hearing loss, atoh1 gene


RefSeq protein



Location UCSC Chr 4: 9383 – 9383 Mb Chr 6: 6473 – 6473 Mb PubMed search 1 2 Wikidata
^ "Mouse PubMed Reference:" 
  • ^ Ben-Arie N, McCall AE, Berkman S, Eichele G, Bellen HJ, Zoghbi HY Sep 1996 "Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis" Human Molecular Genetics 5 9: 1207–16 PMID 8872459 doi:101093/hmg/591207 
  • ^ a b "Entrez Gene: ATOH1 atonal homolog 1 Drosophila" 
  • Further readingedit

    • Helms AW, Johnson JE Mar 1998 "Progenitors of dorsal commissural interneurons are defined by MATH1 expression" Development 125 5: 919–28 PMID 9449674 
    • Dintilhac A, Bernués J Mar 2002 "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences" The Journal of Biological Chemistry 277 9: 7021–8 PMID 11748221 doi:101074/jbcM108417200 
    • Brown NL, Dagenais SL, Chen CM, Glaser T Feb 2002 "Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development" Mammalian Genome 13 2: 95–101 PMC 2262845  PMID 11889557 doi:101007/s00335-001-2101-3 
    • Leonard JH, Cook AL, Van Gele M, Boyle GM, Inglis KJ, Speleman F, Sturm RA Sep 2002 "Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor Merkel cells and Merkel cell carcinoma" International Journal of Cancer Journal International Du Cancer 101 2: 103–10 PMID 12209986 doi:101002/ijc10554 
    • Gazit R, Krizhanovsky V, Ben-Arie N Feb 2004 "Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway" Development 131 4: 903–13 PMID 14757642 doi:101242/dev00982 
    • Leow CC, Polakis P, Gao WQ Nov 2005 "A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma" Annals of the New York Academy of Sciences 1059: 174–83 PMID 16382053 doi:101196/annals1339048 
    • Sekine A, Akiyama Y, Yanagihara K, Yuasa Y Jun 2006 "Hath1 up-regulates gastric mucin gene expression in gastric cells" Biochemical and Biophysical Research Communications 344 4: 1166–71 PMID 16647036 doi:101016/jbbrc200603238 
    • Mutoh H, Sakamoto H, Hayakawa H, Arao Y, Satoh K, Nokubi M, Sugano K Jul 2006 "The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1" Differentiation; Research in Biological Diversity 74 6: 313–21 PMID 16831200 doi:101111/j1432-0436200600074x 
    • Park ET, Oh HK, Gum JR, Crawley SC, Kakar S, Engel J, Leow CC, Gao WQ, Kim YS Sep 2006 "HATH1 expression in mucinous cancers of the colorectum and related lesions" Clinical Cancer Research 12 18: 5403–10 PMID 17000673 doi:101158/1078-0432CCR-06-0573 
    • Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M Jan 2007 "Reciprocal targeting of Hath1 and beta-catenin by Wnt glycogen synthase kinase 3beta in human colon cancer" Gastroenterology 132 1: 208–20 PMID 17241872 doi:101053/jgastro200610031 
    • Du X, Jensen P, Goldowitz D, Hamre KM May 2007 "Wild-type cells rescue genotypically Math1-null hair cells in the inner ears of chimeric mice" Developmental Biology 305 2: 430–8 PMID 17397818 doi:101016/jydbio200702028 
    • Westerman BA, Breuer RH, Poutsma A, Chhatta A, Noorduyn LA, Koolen MG, Postmus PE, Blankenstein MA, Oudejans CB 2007 "Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal homolog 1 ATOH1, HATH1, MATH1 in neuroendocrine tumors" The International Journal of Biological Markers 22 2: 114–23 PMID 17549667 
    • Scheffer D, Sage C, Corey DP, Pingault V Oct 2007 "Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells" FEBS Letters 581 24: 4651–6 PMID 17826772 doi:101016/jfebslet200708059 
    • Shroyer NF, Helmrath MA, Wang VY, Antalffy B, Henning SJ, Zoghbi HY Jun 2007 "Intestine-specific ablation of mouse atonal homolog 1 Math1 reveals a role in cellular homeostasis" Gastroenterology 132 7: 2478–88 PMID 17570220 doi:101053/jgastro200703047 

    External linksedit

    • ATOH1 protein, human at the US National Library of Medicine Medical Subject Headings MeSH
    • ATOH1 and cancer suppression
    • Human ATOH1 genome location and ATOH1 gene details page in the UCSC Genome Browser

    This article incorporates text from the United States National Library of Medicine, which is in the public domain

    atoh1 and merkel cells, atoh1 antibody, atoh1 brain images, atoh1 cerebellum, atoh1 clinical trial, atoh1 cre, atoh1 gene, atoh1 hearing loss, atoh1 intestine, atoh1 mouse

    ATOH1 Information about


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    ATOH1 viewing the topic.
    ATOH1 what, ATOH1 who, ATOH1 explanation

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