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2-Methoxyestrone


2-Methoxyestrone 2-ME1 is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estrone that is formed by catechol O-methyltransferase via the intermediate 2-hydroxyestrone Unlike estrone but similarly to 2-hydroxyestrone and 2-methoxyestradiol, 2-methoxyestrone has very low affinity for the estrogen receptor and lacks significant estrogenic activity

See also

  • 4-Methoxyestradiol
  • 4-Methoxyestrone

References

  1. ^ http://wwwhmdbca/metabolites/hmdb00010
  2. ^ Anna R Hemnes 16 December 2015 Gender, Sex Hormones and Respiratory Disease: A Comprehensive Guide Humana Press pp 32– ISBN 978-3-319-23998-9 
  3. ^ Christian Lauritzen; John W W Studd 22 June 2005 Current Management of the Menopause CRC Press pp 378–379 ISBN 978-0-203-48612-2 
  4. ^ Bhavnani BR, Nisker JA, Martin J, Aletebi F, Watson L, Milne JK 2000 "Comparison of pharmacokinetics of a conjugated equine estrogen preparation premarin and a synthetic mixture of estrogens CES in postmenopausal women" J Soc Gynecol Investig 7 3: 175–83 doi:101016/s1071-55760000049-6 PMID 10865186 

External links

  • Metabocard for 2-Methoxyestrone - Human Metabolome Database




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